NMDAr相关论文
背景偏头痛是一种严重、具有致残性的神经功能障碍。其发病率与致残率呈逐年上升趋势,影响全世界约15%的人口,其中女性发病率高于......
第一部分文献综述脑卒中是威胁全球老年人群生命和健康的常见疾病。卒中后抑郁（Post-stroke depression,PSD）是在卒中后出现的以抑郁......
慢性脑灌注不足（chronic cerebral hypoperfusion,CCH）是血管性认知功能障碍（vascular cognitive impairment,VCI）发生和发展的过程中......
Spinal cord transmit sensory information to the brain through two major pathways: spinothalamic and spinoparabrachial pa......
Neuropsychopharmacology of ketamine as a rapid-acting agent on depression and suicidal ideation in d
Ketamine is classified as a dissociative anesthetic agent for anesthesia and pain control,and used as an experimental to......
Embryonic NMDAR blockade induces anxiety-like behavior by interrupting NMDAR development in both hip
Postnatal NMDA receptor(NMDAR)blockade causes neuronal deficient in adolescence and adult life....
Defects in neural development alter brain circuit formations and may result in lethality,mental retardation or psychiatr......
Essential role of NO signaling pathway in hippocampal CA1 in morphine-associated memory depends on g
OBJECTIVE The nitric oxide(NO)/soluble guanylyl cyclase(sGC)/cGMP-dependent protein kinase(PKG)signaling pathway has bee......
Fuzheng Quxie Decoction Ameliorates Learning and Memory Impairment in SAMP8 Mice by Decreasing Tau H
Hyperphosphorylation of the microtubule-associated protein,tau,is critical to the progression of Alzheimers disease (AD)......
Isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate rec
Introduction: Neutrophil release of NO/ONOO- induces endothelial cell barrier dysfunction in inflammatory acute lung inj......
Long term effects of microwave radiation on the learning and memory and the expression of NMDA recep
Purpose: In the present study, we intended to investigate whether the high power microwave could cause the continuous di......
抗N-甲基-D-天冬氨酸受体(NMDAR)脑炎是近几年发现且越来越受关注的边缘性脑炎的一种，发病机制可能为抗NMDAR抗体干扰兴奋性谷氨酸......
The Relationship between Nmda Receptors and Microwave Induced Learning and Memory Impairment: A Long
Background: Over the past decade, there has been agrowing concern on the impairment of learning and memorycaused bymicro......
Repetitive mild traumatic brain injury (rmTBI;e.g., sports concussions) is common and results in significant cognitive i......
目的疼痛是组织损伤所引起的一种不愉快的主观感觉和情绪体验。长期慢性疼痛的病人通常伴有抑郁、易怒、兴趣缺失、动机行为下降等......
突触可塑性是指突触在神经元持续活动影响下发生的特异性数目、结构和功能的变化,它是学习记忆形成的基础,在神经功能中发挥重要的......
目的探讨儿童抗N-甲基-D-天冬氨酸受体(NMDAR)脑炎的临床特点。方法对2015年4月至12月复旦大学附属儿科医院神经内科收治的15例确......
期刊
In this work,a calculation method of chemical kinetics was established for labeling reaction of 99mTc-N-ethyl-N2S2-meman......
N-methyl-D-aspartate receptor subtype 3A promotes apoptosis in developing mouse brain exposed to hyp
In the present study, 7 day postnatal C57/BL6 wild-type mice (hyperoxia group) and 7 day postnatal N-methyl-D-aspartate ......
目的定量研究安多霖对微波辐射致大鼠脑、心脏和生殖损伤远后效应的治疗作用机制。方法 30只二级雄性Wistar大鼠随机分为正常对照......
目的:观察癫痫清颗粒对戊四唑点燃癫痫大鼠行为学及脑内NMDAR2B和c-fos表达的影响,探讨其抗癫痫的作用机理。方法:腹腔注射戊四唑......
目的:探讨黄芪多糖对血管性痴呆大鼠空间记忆和海马NMDAR1表达的影响。方法:选择血管性痴呆大鼠60只为研究对象,分成对照组和观察......
本研究通过观察兴奋性氨基酸受体拮抗剂对电休克(electroconvulsive therapy, ECT)后Wistar-Kyoto (WKY)抑郁大鼠模型学习记忆和Ta......
With the support by the National Natural Science Foundation of China,Prof.Fei Zhou and his team from the Fourth Military......
Brain cell apoptosis and enhancement of nervous excitability in pregnant rats with high plasma level
Hyperhomocysteinemia is an important risk factor for preeclampsia-eclampsia. This study established a pregnant rat model......
HIV-1感染者常并发神经系统损伤,患者主要表现为运动功能障碍,认知和行为受损等。研究表明,HIV-1多种蛋白参与上述病理过程,其中Ta......
The toxicity of amyloid-beta(Aβ)is strongly associated with Alzheimer’s disease(AD),which has a high incidence in the ......
Cysteine residues 87 and 320 in the amino terminal domain of NMDA receptor GluN2A govern its homodim
N-Methyl-D-aspartate receptors(NMDARs)play a central role in various physiological and pathological processes in the cen......
N-Methyl-D-aspartate receptors(NMDARs)play vital roles in the central nervous system,as they are primary mediators of Ca......
目的探讨N-甲基-D-天冬氨酸受体(NMDAR)在铝影响小鼠学习记忆中的作用。方法健康成年雄性无特定病原体级小鼠40只,随机分为对照组......
甘氨酸是一种结构最简单的氨基酸,在动物体内广泛存在,为一碳、蛋白质、多肽、核苷酸类、卟啉类以及胆盐代谢中的关键物质.甘氨酸......
目的研究慢性铝暴露对脑皮质与外周血淋巴细胞N-甲基-D-天冬氨酸受体1(NMDAR1)的影响,探讨外周血淋巴细胞NMDAR1作为外周血中铝暴......
目的 探讨鞘内注射cAMP反应元件结合蛋白(CREB)反义寡核苷酸(ODN)对坐骨神经结扎小鼠痛行为的影响.方法 鞘内置管成功C57BL/6雄性......
目的观察磷酸化-N-甲基-D-天门冬氨酸受体（P-NMDAR）蛋白在氟中毒大鼠海马神经细胞的表达情况，探讨氟中毒引起神经细胞损伤的机制。方......
目的 探讨N-甲基-D-天冬氨酸受体抗体(NMDA)介导的自身免疫性脑炎的临床、辅助检查特点、治疗方案.方法 分析2014年6月-2017年4月......
目的 研究砷暴露对不同发育阶段小鼠仔鼠海马N-甲基-D-天冬氨酸受体(NMDAR)水平的影响,探讨砷暴露引起学习记忆能力损伤的可能机制......
目的本研究以胃俞募配穴调节功能性消化不良(Functional dyspepsia,FD)大鼠胃运动的中枢作用靶点和分子机制为切入点,通过观察电针......
