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目的：探讨碱性成纤维生长因子（bFGF）在磅脱移行细胞癌（BTCC）中表达的意义。方法：应用免疫组化ABC法对33例BTCC及12例正常膀胱组织中bFGF抗原进行检测。结果：bFGF在正常移行细胞呈阴性表达．在肿瘤细胞、血管内皮细胞、肌细胞中呈阳性表达，且在肿瘤细胞中的过表达率与不同病理分级、临床分期密切相关（P＜0．05），在单发与多发，初发与复发组间无显著性差异（P＞0．05）。结论：bFGF在BTCC浸润转移过程中起重要作用，可为综合治疗提供新途径。
Objective: To investigate the significance of basic fibroblast growth factor (bFGF) expression in psoriatic transitional cell carcinoma (BTCC). Methods: Immunohistochemical ABC method was used to detect bFGF antigen in 33 cases of BTCC and 12 cases of normal bladder tissue. Results: bFGF was negatively expressed in normal transitional cells. In tumor cells, vascular endothelial cells, muscle cells were positive expression, and the overexpression in tumor cells with different pathological grade, clinical stage is closely related (P <0.05), in single and multiple, primary and No significant difference between recurrence group (P> 0.05). Conclusion: bFGF plays an important role in the invasion and metastasis of BTCC, which may provide a new approach for comprehensive treatment.