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背景 标准的血容量(BV)测定技术需要放射性物质和人类白蛋白,实施时耗时费力,在紧急情况下不实用。本文介绍一种更适合于日常应用的替代检测办法。研究设计与方法 预先征得18例加护病房(ICU)患者和79例门诊患者的同意。以放射性铬((51)Cr)标记红细胞、放射性碘(~(125)I)标记白蛋白和荧光素标记HES(FITC-HES)方法测定红细胞容量(RCV)及血浆容量(PV)。由于动脉内皮功能不良(ED)和毛(细)管渗透性导致
Background The standard blood volume (BV) measurement technique requires radioactive material and human albumin, which is time-consuming to implement and impractical in emergencies. This article describes an alternative detection method that is more suitable for everyday use. Study Design and Methods Prior consent was obtained from 18 intensive care unit (ICU) patients and 79 outpatients. Red blood cell (RCV) and plasma volume (PV) were measured by radioactive chromium (51 Cr) labeling of erythrocytes, radioactive iodine (125 I) labeled albumin and fluorescein labeled HES (FITC-HES) Due to arterial endothelial dysfunction (ED) and hair (thin) tube permeability caused