Pivalate-generating prodrugs have been suggested to cause clinically significant hypocarnitinemia.Tenofovir dipivoxil,a ......

Trimethylamine-N-oxide(TMAO)has emerged as a potential biomarker for atherosclerosis and the development of cardiovascul......

A practical chemical synthesis of L-carmtine(1) has been accomplished from(R)-3-chloro-1,2-propanediol((R)-4),which is a......

一种不经分离而同时测定手性对映体的简便方案是非常有趣和有用的。提出一种基于共振瑞利散射(RRS)光谱技术手性识别新方法,利用功......

适度的疲劳,使人感到爽快,吃得好,睡得也好。但是如果长时间持续疲劳,疲惫得甚至步履维艰,那就非入院治疗不可了。所以,疲劳到稍......

Fasting is believed to have a religious context and it was demonstrated in several biblical accounts(The Bible.Samuel 12......

Celiac disease(CD) is manifested by a variety of clinical signs and symptoms that may begin either in childhood or adult......

L-carnitine selective polymers were prepared by molecular imprinting using methacrylic acid as the functional monomer. ......

目的：探讨特发性畸形精子症药物治疗效果及与治疗时间的关系。方法回顾性选择2011年9月至2013年4月就诊于吉林大学第二医院生殖医学......

目的探究小于胎龄儿(SGA)宫外生长发育迟缓(EUGR)与血浆游离肉碱(FC)水平的相关性。方法选择2013年1~12月在佛山市妇幼保健院出生......

目的：探讨左卡尼汀对维持性血液透析治疗的安全用量。方法：选取我院门诊部自2012年7月～2013年7月间收治的维持性血液透析治疗的患者56......

1例56岁女性患者因胸部不适2 d且合并高血压、糖尿病，给予缬沙坦胶囊、琥珀酸美托洛尔缓释片、瑞舒伐他汀钙片、阿司匹林肠溶片、硝......

60年代用葡萄糖－胰岛素－钾（GIK）溶液治疗急性心肌梗塞（AMI）仅取得表面效果；1967年报告的840例多中心试验证明，GIK对AMI患者无益，以致对这种......

肉碱(carnitine)既是肌肉产能所必需的物质,也是长链脂肪酸的转运和乙酰辅酶A通过线粒体所需要的。新近发现小肠粘膜损伤病人可能......

ＩＮＴＲＯＤＵＣＴＩＯＮＬｏｎｇｔｅｒｍｔｏｔａｌｐａｒｅｎｔｅｒａｌｎｕｔｒｉｔｉｏｎ（ＴＰＮ）ｃａｎｆｒｅｑｕｅｎｔｌｙｌｅａｄｔｏｔｈｅｄｅｖｅｌｏｐｍｅｎｔｏｆｈｅｐａｔｉｃｓｔｅａｔｏｓｉｓ．Ａｌｔｈｏｕｇｈｉｔｓｉｎｃｉｄｅｎｃｅｈａｓ... INTRODUCTION Longterm total parenteral nutrition (TPN) canfrequentlyleadtothedevelopmentofhepaticsteatosis. Altho......

AIM: To evaluate the influence of L-carnitine on mental conditions and ammonia effects on patients with hepatic encephal......

AIM: To determine the fasting plasma carnitine ester in patients with celiac disease. METHODS: We determined the fasting......

AIM:To determine the plasma carnitine ester profile inadult patients with ulcerative culitis (UC) and comparedwith heal......

AIM:To assess clinical and endoscopic response to propionyl-L-carnitine hydrochloride(PLC) in colonic inflammatory bowel......

Methanogenic archaea are known as human gut inhabitants since more than 30 years ago through the detection of methane in......

AIM: To identify plasma analytes using metabolomics that correlate with the diagnosis and severity of liver disease in p......

AIM To identify a panel of biomarkers that can distinguish between non-alcoholic fatty liver disease(NAFLD) and non-alco......

Ｐｒｉｍａｒｙｃａｒｎｉｔｉｎｅｄｅｆｉｃｉｅｎｃｙ(ＣＤＳＰ,ＯＭＩＭ:212140)ｗａｓｆｉｒｓｔｄｅｓｃｒｉｂｅｄｉｎ1975ｂｙＫａｒｐａｔｉｅｔａｌ1　Ｔｈｅｐａｔｉｅｎｔｈａｄａｖｅｒｙｌｏｗｂｌｏｏｄｃａｒｎｉｔｉｎｅｌｅｖｅｌ,ｉｎａｄｄｉｔｉｏｎ,ｔｈ Primarycarnitine deficiency (CDSP, OMIM: 212140) wasfirstdescribedin1975byKarpatietal1 Thepatientha......

肉毒碱(carnitine,简称cart)有明显的正性肌力作用,能对抗某些原因引起的心律失常,与毒K合用尚能使毒K引起心律失常的剂量明显增......

肉毒碱(carnitine,1),化学名为3-羟基4-三甲铵丁酸内盐,药用为其盐酸盐(1·HC1),是有广泛生理活性的一种氨基酸内盐,具有促进消化......

Ｅｆｆｅｃｔｏｆａｃｅｔｙ１－Ｌ－ｃａｒｎｉｔｉｎｅｏｎｃｈｏｌｉｎｅａｃｅｔｙｌｔｒａｎｓｆｅｒａｓｅａｃｔｉｖｉｔｙｉｎｓｔｒｅｐｔｏｚｏｔｏｃｉｎ－ｔｒｅａｔｅｄｒａｔｓＭｅｎｇＦａｎｐｉｎｇ；ＹａｎｇＫａｎｇｊｕａｎ；Ｊ．Ｐｒｉｃｋａｅｒｔｓ... Effectofacety1-L-carnitineoncholine acetyltransferase activityinstreptozotocin-treatedratsMengFanping; YangKangjuan......

Objective To investigate the clinical and biochemical metabolic features of 12 patients with systemic primary carnitine ......

[Objective]To study the effect of curcumin on the proteome of HepG2 cells by using two-dimensional electrophoresis and m......

AIM: To compare the effects of chronic supplementationwith l-carnitine (LCT) and dl-carnitine (DLC) on am-monia toxicit......

AIM:To investigate the effects of chronic supplementation with l-carnitine (LCT) on hepatic catabolism of l-alanine. ME......

AIM: To compare the acute effects of l-carnitine (LCT) and dl-carnitine (DLC) on hepatic catabolism of l-alanine and l-g......

AIM: To evaluate the levels of serum carnitine in patients with cancer in digestive organs and to compare them with othe......

AIM: To demonstrate the feasibility of using woodchuck samples on human microarrays, to provide insight into pathways in......

OBJECTIVE: Traditional Korean Chungtaejeon(CTJ) tea is a type of fermented tea, which has received increasing attention ......

Phyllanthus Urinaria L.(PUL) is a traditional Chinese medicine used to treat hepatic and renal disorders. However, the m......

AIM To identify and characterize the protective effect that L-carnitine exerted against an oxidative stress in C2C12 cel......

Carnitine acylcarnitinetranslocase (CACT )deficiency(OMIM 2 12 138)isanautosomalrecessivediseasecausedbymutationsoftheSL......

【目的】识别球孢白僵菌萌发和杀虫毒力相关的标记物。【方法】本研究对7个球孢白僵菌菌株的孢子进行萌发率和对茶毛虫毒力进行测......

[Objective] To study the effects of L-carnitine (LC) on lowering the high blood lipid and antioxidation in hyperlipidemi......

目的:观察肉毒碱棕榈酰转移酶-1(CPT-1)的活性变化在饱和脂肪酸致乳鼠心肌细胞凋亡过程中的作用。方法:应用饱和脂肪酸棕榈酸盐(pa......

A novel hydrochloride quaternary ammonium salt (E)-4-(benzyloxy)-2-(cinnamo- yloxy)-N,N,N-trimethyl-4-oxobutan-1-aminium......

Application of TMS technology in newborn screening has resulted in major expansion of disorder panel for metabolic disea......

目的:环境因素及抗癌药物的使用会导致生精细胞出现凋亡,从而引起男性不育。目前尚缺乏疗效明确的治疗药物。左卡尼汀被用来治疗男......

AIM: To select characteristic endogenous metabolites in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) p......

小肠上皮是难溶性药物口服递送的主要屏障,本研究基于小肠上皮表达的新型有机阳离子转运体2(OCTN2),设计并制备了由肉毒碱修饰的聚......

Oxidative stress is becoming recognized as a key factor in the progression of chronic liver disease(CLD) and hepatocarci......

AIM: To compare the acute effects of l-caitine (LCT) and dl-camitine (DLC) on hepatic catabolism of l-alanine andl-gluta......

目的 探讨早产儿肠外和肠内营养支持期间血游离肉碱和酰基肉碱水平的动态变化及其与营养方式、胎龄和体重增长速度的关系.方法 选......

Throughout the last decade, the use of energy drinks has been increasingly looked upon with caution as potentially dange......

左旋肉碱(L-carnitine,又名左卡尼汀、肉毒碱、维生素BT),是存在于机体组织的一种特殊含氮化合物,化学名L-β-羟基-γ-三甲胺丁酸(......