栓剂治疗放射性直肠炎５０例疗效观察山西省肿瘤医院放疗妇盆科何传泰，李秀峰，麻富卯山西省肿瘤医院药剂科蔡新民，李桂香，阎克里山西省肿瘤医院门诊部阎秀梅，胡若超放射性直肠炎是妇科肿瘤及其他盆腔肿瘤放射治疗中或放射治疗后常见的并发症，目前尚缺乏满意的治疗方法。我院１９８９年２月至１９９１年４月应用自制的栓剂治疗放射性直肠炎５０例，取得较为满意的疗效，现将资料总结分析如下：临床资料５０例均为女性，３４～６４岁，平均４９岁；自觉症状：血便１００％（５０／５０）。下坠感１００％（５０／５０），里急后重感９８％（４９／５０），粘液便８０％（４０／５０）。下腹骶前疼痛２０％（１０／５０）。放疗后至出现直肠炎症状时间（月）：６个月内４例，占８％，７～１２个月２７例，占５４％，１３～１８个月２例，占４％，１９～２４月３例，占６％，２４个月以上８例，占１６％。大便潜血弱阳性（＋）２５例，占５０％，强阳性（＋＋～＋＋＋）２５例，占５０％。直肠镜检情况及外内照射剂量与发病关系见表１、表２。用药方法一、局部用药：清洁灌肠后，将制备的直肠栓剂两枚放入直肠病变上缘或病变上缘及病变中间部位各放一枚，静卧半小时，每日一次１０次为一疗程，一般２ Suppository treatment of radiation proctitis 50 cases of observation Shanxi Provincial Tumor Hospital radiotherapy of women with pelvic cavity He Chuan-tai, Li Xiu-feng, Ma Fu-mao Shanxi Provincial Tumor Hospital pharmacy Cai Xinmin, Li Guixiang, Yan Kerry Shanxi Cancer Hospital Outpatient Department Yan Xiumei, Hu Ruo Chao Radiation proctitis is Gynecologic oncology and other pelvic tumors in radiotherapy or radiation therapy after the common complications, the current lack of satisfactory treatment. Our hospital from February 1989 to April 1991 with homemade suppositories for the treatment of radiation proctitis in 50 cases, and achieved satisfactory results, the data are summarized as follows: Clinical data of 50 cases were female, 34 to 64 years old, with an average of 49 Years old; symptoms: bloody 100% (50/50). Drop feeling 100% (50/50), tenesmus 98% (49/50), mucus will be 80% (40/50). Lower abdominal and presacral pain 20% (10/50). Symptoms of proctitis after radiotherapy time (months): 4 cases within 6 months, 8%, 7 to 12 months in 27 cases, accounting for 54%, 13 to 18 months in 2 cases, 4%, 19 to 24 Month 3 cases, accounting for 6%, 24 months and more in 8 cases, accounting for 16%. Weak positive fecal occult blood (+) 25 cases, accounting for 50%, strong positive (++ ~ +++) 25 cases, accounting for 50%. Rectal examination and external radiation dose and incidence of disease in Table 1, Table 2. Medication method First, the topical medication: After cleaning the enema, the prepared rectal suppository two into the rectum lesions on the edge of the upper edge of the lesion and lesions in the middle of each place a rest for half an hour, once daily 10 times for a course of treatment , Generally 2