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目的:探讨阴道镜直视宫颈多点活检与传统宫颈活检对宫颈疾病诊断的临床应用及影响因素研究。方法:选择2015年5月至2016年3月我院妇科收治的宫颈疾病患者86例,按照随机数表法,将患者分为对照组和研究组,每组43例。对照组患者进行常规的宫颈活检,研究组患者采用阴道镜直视宫颈多点活检。对比两种检查方法与病理检查结果的检出率,并比较两种检查方法的漏诊率,另外考察影响阴道镜直视宫颈多点活检漏诊率的相关因素。结果:与病理检查结果相比,除宫颈炎和宫颈癌外,研究组对其他类型宫颈疾病的检出率及总检出率明显高于对照组(P<0.05);除宫颈癌外,研究组对各种宫颈疾病的漏诊率与对照组相比明显下降(P<0.05);年龄超过50岁,高级别的CIN类型、标本个数的减少及宫颈微小病变都可能升高阴道镜直视宫颈多点活检漏诊率。结论:与传统宫颈活检相比,阴道镜直视宫颈多点活检对宫颈疾病的诊断具有较高的诊断率,并且漏诊率较低,可以适当增加活检的样本个数来降低漏诊率,从而尽早发现并进行有效治疗,值得在临床上推广应用。
Objective: To investigate the clinical application of colposcopy and multi-point biopsy of cervix and cervical biopsy on the diagnosis of cervical disease and its influencing factors. Methods: From May 2015 to March 2016, 86 cases of cervical diseases admitted to our hospital were divided into control group and study group according to random number table method, with 43 cases in each group. Patients in the control group underwent routine cervical biopsies. The study group underwent colposcopy biopsy with colposcopy. Compare the detection rate of the two methods and the pathological examination results, and compare the rate of misdiagnosis between the two methods. In addition, investigate the related factors which influence the misdiagnosis rate of colposcopy biopsy. Results: Compared with the results of pathological examination, in addition to cervicitis and cervical cancer, the study group of other types of cervical disease detection rate and the total detection rate was significantly higher than the control group (P <0.05); except for cervical cancer, the study The rate of misdiagnosis of various cervical diseases was significantly lower than that of the control group (P <0.05). Patients over 50 years of age with high-grade CIN types, decreased number of specimens and minimal cervical lesions were likely to have increased colposcopy Multiple cervical biopsy missed diagnosis rate. Conclusion: Compared with traditional cervical biopsy, colposcopy multicenter cervical biopsy has high diagnostic rate of cervical disease diagnosis, and the low rate of missed diagnosis, the number of biopsies can be increased appropriately to reduce the rate of missed diagnosis, so as soon as possible Discovery and effective treatment, it is worth to promote the clinical application.