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人和家兔感染肝片吸虫可用免疫扩散、免疫电泳和对流免疫电泳等方法探测沉淀素抗体,作者报告了以二碘水杨酸酰替苯胺(rafoxanide)每公斤体重50毫克治疗家兔后的免疫学变化。实验组Ⅰ:以从波多黎各野外的椎实螺检获的肝片吸虫后囊蚴感染4只家兔,1号兔感染11个后囊蚴,于感染后0,4,7,9,11及16周采血,感染后11周用二碘水杨酸酰替苯胺单次量治疗,2,3,4号兔各感染6个后囊蚴,于感染后0,4,6,7和10周采血(3号兔12周采血),感染后6周,2,3号兔用二碘水杨酸酰替苯胺治疗,4号兔作对照。全部家兔剖检寻找成虫,收集所有血样本贮存于-75℃。
Human and rabbit infected with Fasciola hepatica can be immunodiffusion, immunoelectrophoresis and convective immuno-electrophoresis and other methods to detect precipitin antibodies, the authors report the use of diiodosalicylamide (rafoxanide) 50 mg per kg body weight after treatment of rabbits Immunological changes. Experimental group I: Four rabbits were infected with the metacercariae of Fasciola hepatica seized from the spines of Puerto Rico and 11 rabbits were infected with 11 metacercariae at 0, 4, 7, 9, 11 and 16 post-infection Blood samples were taken from the rats and were treated with diiodo-salicylic acid anilide for 11 weeks after infection. Rabbits 2, 3 and 4 were each infected with 6 metacercariae and blood was taken at 0, 4, 6, 7 and 10 weeks after infection (Rabbit 3 rabbits blood 12 weeks), 6 weeks after infection, 2,3 rabbits with diiodo salicylic acid for aniline treatment, rabbits as a control. All rabbits were necropsied to find adults and all blood samples were collected for storage at -75 ° C.