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目的分离并鉴定北五味子藤茎的化学成分。方法采用硅胶柱色谱、凝胶柱色谱、氧化铝柱色谱和重结晶等多种分离方法,对北五味子藤茎体积分数为95%乙醇的冷浸提取物进行分离,并通过NMR等多种方法对分离得到的化合物进行结构鉴定。结果分离得到8个化合物,分别鉴定为(-)schisandrin B(1)、五味子醇B((+)-schizandrol B,2)、五味子素C((-)-schisandrinc,3)、五味子甲素((+)-deoxyschizandrin,4)、(+)-gomisin M1(5)、(-)-dihydroguaiaretic acid(6)、(-)-aus-trobailiguan6(7)、尿嘧啶(uracil,8)。结论化合物5~8为首次从北五味子藤茎中分离得到。
Objective To isolate and identify the chemical constituents of the cane of Schisandra chinensis. Methods A variety of separation methods such as silica gel column chromatography, gel column chromatography, alumina column chromatography and recrystallization were used to separate the cold-dipping extracts of cane with a volume fraction of 95% ethanol and to pass NMR and other methods. The isolated compound was structurally identified. Results Eight compounds were isolated and identified as (-) schisandrin B (1), schizandrol B ((+)-schizandrol B, 2), schisandrin C ((-)-schisandrinc, 3), and schizandrin ( (+)-deoxyschizandrin, 4), (+)-gomisin M1 (5), (-)-dihydroguaiaretic acid (6), (-)-aus-trobailiguan6 (7), uracil (8). Conclusion Compounds 5-8 were isolated from the cane of Schisandra chinensis for the first time.