论文部分内容阅读
目的:研究注射用喜炎平的药理作用。方法:进行了体内抗菌试验,解热试验,抗炎试验及止咳试验。结果:注射用喜炎平对金黄色葡萄球菌、肺炎链球菌感染小鼠有明显的保护作用,其ED50分别为389.2mg/kg、475.9mg/kg;有明显的解热、抗炎作用;对枸橼酸致豚鼠咳嗽次数有明显抑制作用。结论:注射用喜炎平具有清热解毒,抗菌消炎,止咳的药理作用。
Objective: To study the pharmacological effects of Xiyanping for injection. Methods: In vivo antibacterial test, antipyretic test, anti-inflammatory test and cough test were conducted. RESULTS: Xiyanping injection had significant protective effect against Staphylococcus aureus and Streptococcus pneumoniae infection in mice. Its ED50 was 389.2mg/kg and 475.9mg/kg respectively. It had obvious antipyretic and anti-inflammatory effects. The citric acid induced guinea pig cough frequency has a significant inhibitory effect. Conclusion: Xiyanping injection has the pharmacological effects of heat-clearing, detoxifying, antibacterial, anti-inflammatory and cough relieving.