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阑尾切除术曾被认为是溃疡性结肠炎(UC)的保护因素。研究旨在阐明阑尾切除术在炎症性肠病(IBD)中所起的作用。 病人与方法:1984年至1991年1月1日确诊的UC或CD病人列为现患病例组(UC 232例,CD 208例);另将1991～1994年确诊并在IBD中心登记过的UC或CD病人列为新发病例组(UC 191例,GD 136例)。对照组均无IBD病史。收集有关疾病特征和炎症部位的医学资料,再通过调查表获得病人组和对照组的吸烟情况、是否有阑尾切除术史及其时间。 结果:在232例现患UC病例中,其阑尾切除术后患UC的危险度显著下降(OR为0.36,95％CI为0.15～0.8);亚组分析发现这种保护
Appendectomy has been considered a protective factor for ulcerative colitis (UC). The aim of the study was to elucidate the role of appendectomy in inflammatory bowel disease (IBD). PATIENTS AND METHODS: Patients with UC or CD diagnosed between January 1984 and January 1, 1991 were enrolled in the current case group (232 cases of UC, 208 cases of CD). Patients who were diagnosed from 1991 to 1994 and registered in the IBD center UC or CD patients were classified as new cases (UC 191 cases, GD 136 cases). The control group had no history of IBD. Collect medical information about the disease characteristics and the site of inflammation, and then obtain the smoking status of the patient group and the control group by the questionnaire, whether there is appendectomy history and the time. Results: The risk of UC after appendectomy was significantly lower in 232 patients with pre-existing UC (OR 0.36; 95% CI 0.15-0.8); subgroup analysis found this protection