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已发现异位性皮炎和呼吸系变态反应患者的血清类脂中的脂肪酸成分有异常,表现为亚油酸含量增高、花生四烯酸和亚油酸的其它代谢产物降低.为进一步阐明必需脂肪酸的改变与特应性的关系,作者按Olegard和Svenner-Holm介绍的方法,测定了异位性皮炎儿童血清和具有IgE水平升高或降低的新生儿脐血清卵磷脂中的脂肪酸含量.结果与107名年龄相匹配的对照组比较,9例异位性皮炎儿童的血清亚油酸水平显著增高(P<0.001),2-同
It has been found that patients with atopic dermatitis and respiratory allergy serum lipid abnormalities in the composition of fatty acids, showed increased linoleic acid content, arachidonic acid and other linoleic acid metabolites decreased.In order to further clarify the essential fatty acids Of the changes associated with atopic, the authors according to Olegard and Svenner-Holm introduced the method of determination of atopic dermatitis and serum IgE levels with elevated or decreased neonatal cord serum lecithin fatty acid content.Results Serum linoleic acid levels were significantly increased in 107 age-matched control subjects (P <0.001), and in 9 children with atopic dermatitis