报道了烟酰肼与取代芳醛反应生成相应的烟酰芳腙在醋酐催化下生成 2 -芳基 - 3-乙酰基 - 5 - (吡啶 - 3-基 ) - 1,3,4二唑啉 ,不经分离直接与碘甲烷作用生成相应的季铵盐 ,接着用硼氢化钠还原季铵化物而得含四氢吡啶环和唑啉环的新化合物 3- (2 -芳基 - 3-乙酰基 - 1,3,4 -二唑啉 - 5 -基 ) - 1,1-二甲基 - 1,2 ,5 ,6 -四氢吡啶碘化物 ,其结构经 IR、1 HNMR、MS和元素分析确证 The reaction of nicotinyl hydrazide with substituted aryl aldehydes to give the corresponding nicotinoid arylhydrazones was reported to be the most efficient way to produce 2 - aryl - 3 - acetyl - 5 - (pyridin - 3 - yl) The oxazoline can be directly reacted with methyl iodide to form the corresponding quaternary ammonium salt without separation, and then the quaternary ammonium compound can be reduced with sodium borohydride to obtain the novel compound 3- (2-aryl- 3-acetyl-1,3,4-diadiazolin-5-yl) -1,1-dimethyl-1,2,5,5-hexahydropyridine iodide, its structure was confirmed by IR, 1 H NMR , MS and elemental analysis confirmed