cytotox相关论文
The present study was designed to perform structural modifications of of neobavaisoflavone (NBIF),using an in vitro enzy......
Scapaundulin C, a novel labdane diterpenoid isolated from Chinese liverwort Scapania undulate, inhib
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Type IV collagenase plays an important role in tumor invasion and metastasis through cleaving type IV collagen in the b......
Necroptosis is characterized by programmed necrotic cell death and autophagic activation and might be involved in the de......
目的 探讨百里醌(TQ)对非小细胞肺癌(NSCLC)细胞毒性作用的分子机制.方法 NSCLC鳞癌细胞SK-MES-1接种于96孔板,予20、40、60、80、......
AM: To examine an association between the cytotoxic T-lymphocyte antigen 4 (CTLA4) gene that plays a role in downregulat......
Inflammatory bowel disease(IBD)includes two similar yet distinct conditions called ulcerative colitis(UC)and Crohn’s di......
Objective To improve the compound--Gankang granules(GKGs) on the odor,taste and efficacy by decreasing 30% components an......
Hepatitis B virus(HBV) infection has received increasing public attention. h BV is the prototypical member of hepadnavir......
Apoptosis is a form of genetically programmed cell death, which plays a key role in regulation of cellularity in a varie......
EFFECTS OF GINSENOSIDE ON THE NATURAL KILLER CELL-INTERFERON-INTERLEUKIN-2 REGULATORY NETWORK AND IT
It is well established that natural killer cells(NKC)are the body’s first line of defense againstmalignant growth, and......
A continuing phytochemical study on the semi-mangrove plant Hibiscus tiliaceus yielded two new tetracyclic triterpenoids......
Phenolics-saponins rich fraction of defatted kenaf seed meal exhibits cytotoxicity towards cancer ce
Objectives: To determine the cytotoxicity of crude ethanolic extract, n-butanol fraction and aqueous fraction on selecte......
In the present study,67 cases of hepatocellular carcinoma(HCC)were treated withimmunotherapy or immunochernotherapy.The......
Triptolide(TPL/TL) is a natural drug with novel anticancer effects. Preclinical studies indicated that TPL inhibits cell......
,Preparation and in vitro cytotoxicity study of poly (aspartic acid) stabilized magnetic nanoparticl
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Synthesis and in vitro biological evaluation of farnesylthiosalicylic acid derivatives as anti-tumor
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 探讨幽门螺旋杆菌(helicobacter pylori,HP)感染与线粒体DNA(mitochondrial DNA,mtDNA)碱基突变之间的关系.方法 HP11638(Cag......
我们观察了209例慢性乙型肝炎(CHB)住院患者进展为慢性重型乙型肝炎前、后的HBV特异性细胞毒性T淋巴细胞(CTL)、非特异性CTL、T淋......
目的：评价不饱和聚磷酸酯（UPPE）聚合物对小鼠胚胎颅顶骨MC3T3－E1成骨细胞的毒性影响。方法：将β－磷酸三钙（β－TCP）、UPPE聚合物分别与小鼠胚......
量子点因其具有独特的物理和化学性质（如激发光谱宽、发射光谱窄，而且可通过改变量子点内核心材料的尺寸大小对其发射光波长进行调频......
Poly(ethylenimine)-grafted-poly[(aspartic acid)-co-lysine]:A Non-viral Polymer with Potential for DN
A biodegradable gene transfer vector, poly(ethylenimine)-grafted-poly[(aspartic acid)-co-lysine] has been developed by t......
目的：制备去甲斑蝥素纳米粒（norcantharidin nanoparticles,NCTD-NP）,并考察其缓释特性和细胞毒性。方法：以聚乳酸-聚乙二醇为载体,采......
目的研究幽门螺杆菌（Hp）感染相关性胃炎胃黏膜组织细胞毒素相关蛋白A（CagA）表达,3种炎性因子水平的变化及关系。方法选体检中心50名健......
RESPONSES OF HUMAN FETAL SPLENOCYTES AND THYMOCYTES TO INTERLEUKIN-2: LAK ACTIVITY AND PROLIFERATION
Using cytotoxicity and thymidine uptake assays, we investigated the effects of human recombinant in-terleukin-2 (rIL-2) ......
目的探讨Genistin对β淀粉样蛋白片段(Aβ1-42)诱导的PC12细胞损伤的神经保护作用.方法将培养的PC12细胞分为:正常对照组、Aβ1-42......
实验取正常鼠和Ｐ８１５肿瘤细胞致敏的免疫鼠脾细胞，经抗ＣＤ３抗体与低剂量ＩＬ－２或高剂量ＩＬ－２分别诱生为ＣＤ３ＡＫ细胞和ＬＡＫ细胞，用改良的乳酸脱氢酶释放法以Ｐ８１５细胞和ＹＡＣ－１细胞......
目的探讨自然杀伤NK细胞杀瘤活性与肿瘤细胞表面MICA/B表达的相关性。方法采用流式细胞术检测人红白血病细胞K562、乳腺癌细胞Bcap......
目的 了解ＣonA在体内对小鼠腹腔Ｍф吞噬功能、细胞毒作用及产生NO、TNF-α、IL-1的影响。方法 分别测Mф吞噬鸡红细胞的能力，以S180为......
以表面修饰巯基十一烷酸的金纳米棒(GNRs/MUA)为骨架,将低分子量的聚乙烯亚胺(PEI)连接到GNRs/MUA表面,构建GNRs/MUA/PEI纳米载体......
目的：构建结核分枝杆菌MycP1蛋白原核表达系统。方法：构建pGEX-4T-1-Rv3883c重组质粒,转化大肠杆菌,经IPTG诱导表达,采用SDS-PAGE和W......
从体内抑制试验和体外培养巨噬细胞的杀瘤试验对甲鱼组织浆的抑瘤作用进行了研究。体内抑瘤试验采用组织浆灌胃方式，计算抑瘤率和生......
将低聚壳聚糖（COS）分别与不同卟啉金属（MTPPS4，M=Cu，Co，Zn）配合物结合，制备了水溶性低聚壳聚糖负载金属卟啉配合物（COS-MTPPS4），并采用红外光......
目的探讨细胞毒蛋白:T细胞内抗原(TIAI)和丝氨酸蛋白酶-粒酶B(G ranzyme B)在鼻NK/T细胞淋巴瘤中的表达及临床意义.方法对17例鼻NK......
<正>In order to investigate the effect of different C4 linkage moieties on the cytotoxicity of podophyllotoxin derivativ......
A new sesquiterpene（Z）-7-acetoxy-methyl-11-methyl-3-methylenedodeca-1,6,10-triene（AMDT） was isolnted and identified from the......
目的:探讨幽门螺杆菌细胞毒素相关基因蛋白(Cag A)抗体与消化性溃疡和慢性胃炎的关系.方法:对132例消化性溃疡和慢性胃炎Hp幽门螺......
用色谱技术对海南大风子（Hydnocarpus hainanensis（Merr.）Sleum.）枝条的乙醇提取物进行分离纯化,从中分离得到了6个化合物,经波谱数据......
目的：建立从20mL外周血中高效扩增抗CD3单克隆抗体激活的杀伤细胞（CD3AK）的培养体系,并进行体外细胞毒活性检测。方法：采用抗CD3单克隆......
树突状细胞(DC)是目前发现的功能最强的抗原呈递细胞,其在肿瘤免疫临床治疗中的应用受到越来越多的关注.目前,通过各种方法提取肿......
目的:通过奥美拉唑对胃癌上皮细胞、幽门螺杆菌(Hp)菌株生长及空泡毒素(VacA)毒性的影响,探讨其临床应用价值.方法:应用不同浓度奥......
报道尿苷２－烷基（酰基）－１，３－甘油硫代环磷酸酯的合成，用碘活化的六乙基亚磷酰三胺作为磷酸化试剂，分离得到了硫代环磷酸酯的两个顺反异构体。初......
首先介绍了超声作用的物理机理和血卟啉及其衍生物的化学结构及物理化学性质,对超声激活血卟啉抗肿瘤疗法(声动力学疗法)近15年国......
目的：通过特异性细胞毒性T淋巴细胞（CTL）与IL-21共同作用daudi细胞，观察CTL与IL-21对daudi细胞的作用机制。方法培养肿瘤特异性CTL细胞......
