apatinib相关论文
研究背景:恶性肿瘤严重威胁着我国居民的生命健康,化疗是恶性肿瘤治疗的主要手段之一,但目前限制化疗药物（例如紫杉醇或喜树碱）临床......
目的:验证阿帕替尼联合奥沙利铂+替吉奥(SOX)方案在晚期胃癌伴腹膜转移患者中的转化治疗疗效。方法:采用描述性病例系列研究方法，收......
目的 探讨在晚期胰腺癌患者临床治疗中应用替吉奥联合阿帕替尼治疗的临床价值。方法 将62例本院于2015年6月至2017年12月收治的晚......
目的:探讨肝动脉化疗栓塞(TACE)联合阿帕替尼治疗中晚期肝癌的效果和安全性。方法:抽取2019年6月至2020年6月郑州大学第一附属医院......
目的:总结应用阿帕替尼治疗消化道肿瘤致患者口腔黏膜炎的护理经验。方法:2020年6月至2021年6月中山大学附属第三医院岭南医院普外......
目的 Apatinib,a small molecule inhibitor of VEGFR-2 tyrosine kinase,shows stronganti-tumour activityagainst various tumo......
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Apatinib for patients with sorafenib-refractory advanced hepatocellular carcinoma:Results of a pilot
Objective Background: More than half of patients with advanced hepatocellular carcinoma(HCC)do not respond to primary tr......
How to choose the third-line treatment for advanced gastric or gastroesophageal junction cancer:An i
Objective Although apatinib,immune checkpoint inhibitors,and trifluridine/tipiracil have shown promising results in phas......
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Apatinib plus docetaxel or pemetrexed shows promising activities against NSCLC with brain metastasis
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Objective Apatinib is an oral small-molecule tyrosine kinase inhibitor(TKI)that selectively binds to and inhibits VEGFR2......
Efficacy and safety of apatinib with or without radiotherapy as second-line or beyond therapy in pat
Objective Apatinib is the first small-molecule anti-angiogenic targeting drug that has been proven safe and effective in......
Multi-targeted tyrosine kinase inhibitors as third-line regimen in advanced non-small cell lung canc
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Importance of Apatinib and Re-irradiation in Salvage Therapy:a Analysis of 80 Patients With Recurren
Objective Glioma is a primary malignant tumor that originates in the glial cells of the brain.The incidence rate is incr......
TACE combined with apatinib versus TACE alone for hepatocellular carcinoma with macroscopic vascular
Objective Macroscopic vascular invasion of hepatocellular carcinoma(HCC),including portal vein tumor thrombosis(PVTT)or ......
Phase Ⅱ trial of apatinib plus chemotherapy for second-line and above treatment of advanced SCLC:foc
Objective Lung cancer is the most common malignancy in the world and is especially prevalent in China,as a highly aggres......
Apatinib combined with Vinorelbine in Second Line Treatment Failure non-driver Mutation Advanced Non
Objective Lung cancer is the leading cause of cancer related death worldwide.There is currently no standard treatment st......
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Efficacy and Safety of the VEGFR2 Inhibitor Apatinib for Metastatic Soft Tissue Sarcoma: Chinese Coh
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Combining transcatheter arterial embolization with iodized oil containing Apatinib inhibits HCC grow
Objective Transcatheter arterial embolization(TAE)is playing a major role in the treatment of advanced liver cancer.Howe......
Apatinib inhibits cell proliferation and induces autophagy via the PI3K/Akt signaling pathway in hum
Objective Objective: PTC is the most common type of thyroid cancer and has a favorable prognosis.However,patients with m......
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A case of locally advanced gastric cancer treated with preoperative SOX chemotherapy plus Apatinib f
Objective We report the case of a 52-year-old male who was diagnosed with locally advanced gastric cancer and treated wi......
Successful treatment of advanced pancreatic liposarcoma with apatinib:a case report and literature r
Pancreatic liposarcoma is a malignant tumor originated from the pancreas mesenchymal tissue and mostly presented in skin......
Objective:No definitive chemotherapeutic regimen has been established in patients with non-small cell lung cancer(NSCLC)......
Prospective, multicenter, non-interventional and registry clinical study of apatinib in patients wit
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Objective Treatments for stage Ⅳ gastric cancer shown in guideline are palliative and supportive care,but some studies ......
Effectiveness and safety of Apatinib combined with SOX regimen for conversion therapy of initial unr
Objective To observe the effectiveness and safety of Apatinib combined with SOX regimen for cT4bN1-N3M0 initial unresect......
目的 探讨阿帕替尼联合化疗治疗晚期胃癌疗效观察。方法 选取2018年10月至2019年10月92例晚期胃癌患者为研究对象，根据随机抽签法分......
目的 观察阿帕替尼对恶性胸腔、腹腔积液的临床疗效。方法 选择恶性胸腔、腹腔积液患者共40例，随机分为两组，各20例。试验组患者采用......
Phase Ⅱ study of apatinib in combination with oral vinorelbine in heavily pretreated HER2-negative m
Objective:Apatinib is an oral TKI targeting VEGFR-2.Single-agent apatinib treatment has been shown to produce an objecti......
目的探究甲磺酸阿帕替尼单药以及联合吉西他滨三线化疗对非小细胞肺癌(NSCLC)的疗效和不良反应。方法对2017年5月至2019年5月汉中......
Efficacy and adverse reactions of apatinib as secondline or later-line treatment in advanced lung ca
Objective The objective was to investigate the prognostic factors of advanced lung cancer treated with apatinib by log-r......
食管癌是我国发病率及死亡率较高的消化道常见恶性肿瘤之一，现阶段以手术、放疗、化疗等综合治疗为主。近年来，抗血管生成治疗在多种......
Phase Ⅱ study of apatinib in combination with oral vinorelbine in heavily pretreated HER2-negative m
Objective: Apatinib is an oral TKI targeting VEGFR-2. Single-agent apatinib treatment has been shown to produce an objec......
Efficacy and adverse reactions of apatinib as second-line or later-line treatment in advanced lung c
Objective The objective was to investigate the prognostic factors of advanced lung cancer treated with apatinib by log-r......
肺癌是全球病死率最高的恶性肿瘤,晚期肺癌生存率更低.目前对于无驱动基因突变的肺癌,标准治疗方案为化疗,但疗效欠佳,生存获益低,......
目的 评价阿帕替尼联合化疗一线治疗Ⅳ期软组织肉瘤的疗效与安全性.方法 回顾性分析8 例Ⅳ期软组织肉瘤一线接受阿帕替尼联合化疗......
目的探讨阿帕替尼(Apatinib)对体外培养的胰腺癌AsPC-1细胞增殖、凋亡、迁移的影响。方法以不同浓度Apatinib干预胰腺癌AsPC-1细胞......
1例45岁男性结肠癌患者术后化疗服用甲磺酸阿帕替尼片500 mg、1次/d。用药第19天，患者出现下腹间歇性疼痛、恶心、呕吐、纳差、乏力......
1例29岁男性肾上腺恶性嗜铬细胞瘤患者口服甲磺酸阿帕替尼500 mg、1次/d，1周后因血压升高减量至375 mg、1次/d。服药第37天患者排血......
1例68岁男性患者因进展期胃癌伴肝转移、淋巴结转移经多线治疗出现骨髓抑制而给予阿帕替尼850 mg口服，1次/d。服药约1个月，患者出现......
