S-adenosylmethionine相关论文
Cloning, overexpression, characterization of thermo-stabile S-adenosylmethionine synthetase from The
S-Adenosylmethionine(SAM)is the important methyl donor in the cells.The function of SAM is involved in gene transcriptio......
S-adenosylmethionine(SAM) is an essential regulatory compound in many biological reactions and an active small molec......
Important role of N-terminal kinase domain of protein kinase AfsK in S-adenosylmethionine (SAM)-medi
S-Adenosylmethionine (SAM) is a well-known methyl donor for the methylation of nucleic acids,proteins,and small mole......
Important Role of N-terminal Kinase Domain of Protein Kinase AfsK in S-adenosylmethionine (SAM)-medi
S-Adenosylmethionine (SAM) is a well-known methyl donor for the methylation of nucleic acids,proteins,and small mole......
1例64岁男性患者，因乙型肝炎后肝硬化失代偿期，静脉注射丁二磺酸腺苷蛋氨酸1 000 mg和静脉滴注异甘草酸镁200 mg，1次/d。患者用药前心......
目的 初步明确肝癌细胞中特异性表达缺失的GADD45β基因近端启动子活性调控中心,并探讨S腺苷蛋氨酸对肝癌细胞HepG2中GADD45β表达......
目的通过观察S-腺苷蛋胺酸(SAM)对胃癌细胞(MGC803、SGC7901细胞株)、裸鼠移植瘤生长的影响,以及对胃癌细胞株血管内皮生长因子-C(......
目的：探讨腺苷蛋氨酸治疗脓毒血症患者对肝脏的保护作用。方法将60例脓毒血症患者随机分为观察组和对照组各30例，观察组在早期加用腺......
目的：探讨束缚应激对肝脏S-腺苷甲硫氨酸（SAM）和S-腺苷同型半胱氨酸（SAH）代谢的影响。方法Wistar大鼠16只随机均分为对照组和束缚应激组......
目的 评价熊去氧胆酸(UDCA)与S-腺苷蛋氨酸(SAMe)联合及单独使用改善妊娠肝内胆汁淤积症(ICP)妊娠结局的疗效和安全性. 方法 计算......
Inhibitory effect of S-adenosylmethionine on the growth of human gastric cancer cells in vivo and in
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 观察p53对肝癌细胞GADD45β诱导的影响并探讨其机制.方法 转染p53全序列建立Hep3B~(+p53);比较S腺苷蛋氨酸对Hep3B~(+p53)的G......
Inhibitory effect of S-adenosylmethionine on the growth of human gastric cancer cells in vivo and in
Background and Objective: S-adenosylmethionine(SAM),the most important methyl donor in human body,is generally used to t......
目的 观察腺苷蛋氨酸(SAMe)治疗白毒伞中毒的临床疗效.方法 回顾性分析12例白毒伞中毒病例资料,按是否使用SAMe治疗分为两组:A组接......
目的分析S-腺苷蛋氨酸联合利胆药对妊娠期肝内胆汁淤积症产妇胎盘组织中NF-κB相关因子表达水平及Th17/Treg平衡的影响。方法选取2......
目的研究腺苷蛋氨酸对经动脉栓塞化疗（TACE）术后肝功能的保护作用。方法 2010年3月1日～2010年10月23日在湘雅医院进行TACE治疗的63例......
从本实验室建立的小金海棠缺铁差减文库中分离出一个cDNA片段，在GenBank中发现该片段与其它植物的S-腺苷甲硫氨酸合成酶（SAMS）基因具......
对摇瓶发酵生产富含S-腺苷甲硫氨酸的面包酵母的培养条件和培养基成分进行了优化，单因子实验结果表明，发酵最适pH值为5．0，最适装液量为......
以插入AOXl启动子调控S-腺苷甲硫氨酸（SAM）合成酶／VHb表达单元的重组毕赤酵母为对象，研究了甲醇浓度及vgb表达对菌体生长、SAM产量及SA......
Nonalcoholic fatty liver disease(NAFLD)is a heterogeneous and complex disease that is imprecisely diagnosed by liver bio......
摘要优化了重组毕赤酵母表达的S-腺苷甲硫氨酸合成酶催化L-甲硫氨酸（Met）和ATP合成S-腺苷甲硫氨酸的条件，确定了该酶的最适酶活力检测......
建立了用高效液相色谱同时测定Pichia pastoris菌体中腺苷甲硫氨酸及其代谢相关物质（AMP，腺苷，腺嘌呤，SAH）。采用Hypersil SCX色谱柱（4．6m......
Prostate Specific Antigen Promoter-Driven Adenovirus-Mediated Expression of Both ODC and AdoMetDC An
目的将产生能同时在前列腺癌症房间明确地表示鸟氨酸 decarboxylase (ODC ) 和 S-adenosylmethionine decarboxylase (AdoMetDC ) ......
S-adenosylmethionine in treatment of cholestasis after total parenteral nutrition: laboratory invest
【正】 Objective: To observe the effects of S-adenosylmethio-nine (SAMe) in the treatment of cholestasis after totalpare......
AIM To investigate the hypothesis that exposure to guanidinoacetate(GAA, a potent methyl-group consumer) either alone or......
Methionine adenosyltransferases(MATs)are essential enzymes for life as they produce S-adenosylmethionine(SAMe),the biolo......
以高产拿腺苷甲硫氨酸的菌株Saccharomyces cerevisiae B9对培养基和发酵条件进行了优化研究。通过单因素水平测试和正交水平测试，......
目的：探讨癌基因启动子区域重新甲基化对胃癌细胞生长的影响。方法：用S-腺苷甲硫氨酸（SAM）使胃癌细胞系MGC-803中癌基因H—ras启动子区......
目的探讨间断给予S-腺苷蛋氨酸（SAMe）对二乙基亚硝胺（DEN）诱发大鼠肝癌的保护作用。方法将36只雄性SD大鼠随机分为3组,各12只。观察组......
目的筛选产腺苷蛋氨酸（SAM）的酵母菌并进行诱变育种。方法以选择性培养基筛选酵母菌株并用高效液相色谱检测SAM。利用紫外线和γ-射......
目的观察腺苷蛋氨酸联合苦参碱治疗病毒性肝炎高胆红素血症的临床疗效。方法将病毒性肝炎高胆红素血症患者120例随机均分为治疗组......
Inhibitory effect of S-adenosylmethionine on the growth of human gastric cancer cells in vivo and in
Background and Objective: S-adenosylmethionine (SAM), the most important methyl donor in human body, is generally used t......
建立了同时检测大鼠肝脏中S-腺苷甲硫氨酸(SAM)和S-腺苷同型半胱氨酸(SAH)的高效液相色谱-串联质谱法。肝脏样品匀浆后用5.0 mmol/......
目的:探讨S-腺苷蛋氨酸联合熊去氧胆酸的作用,对妊娠期肝内胆汁淤积症的治疗效果影响。方法:妊娠期肝内胆汁淤积症患者170例按照随......
S-腺苷甲硫氨酸（S-adenosyl-L-methionine，SAM）是一种需求量巨大的活性氨基酸。SAM生产主要是利用过表达甲硫氨酸腺苷转移酶（methionin......
建立了利用Waters2695高效液相色谱测定毕赤酵母发酵液中S-腺苷蛋氨酸（S-adenosylmethionine，SAM）含量的方法，对HPLC—UV法检测SAM含量......
目的观察S-腺苷甲硫氨酸对血小板源性生长因子mRNA表达及对血管平滑肌细胞(VSMCs)增殖与迁移的影响。方法于2015年3月—2016年3月......
目的研究小剂量普通肝素治疗重度慢性乙型肝炎的疗效和安全性。方法将70例重度慢性乙型肝炎患者分为三组，对照组25例予常规护肝退黄......
Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A system
BACKGROUND S-adenosylmethionine(AdoMet)is a metabolically pleiotropic molecule used to treat intrahepatic cholestasis(IH......
A Prospective, Open-Label, 12 Week Trial of S-adenosylmethionine in the Symptomatic Treatment of Alz
Objective: To determine if treatment with S-adenosylmethionine (SAM-e) might lead to cognitive and behavioral improvemen......
