CONNEXIN相关论文
Connexin therapeutics: blocking connexin hemichannel pores is distinct from blocking pannexin channe
Compounds that block the function of connexin and pannexin protein channels have been suggested to be valuable therapeut......
Aim: To explore the mechanism of chronic renal failure (CRF)-related erectile dysfunction (ED). Methods: CRF experimenta......
Purpose To identify the pathogenic mutation responsible for autosomal dominan congenital cataract(ADCC)in a Chinese pedi......
Connexin 26 and connexin 43 between excitatory neurons differentially impact neural synchronous acti
Previous studies have shown that excitatory neurons form transient gap junctions with each other at early postnatal stag......
Aim: Previous findings from our laboratory have shown that exposure to inflammation stimuli induced by lipopolysaccharid......
Objective To identify the cataract-causing mutations in a Chinese family and primitively determine themechanism underlyi......
Aim To identify the mutations associated with congenital cataract in a Chinese family and study the functional effects o......
The impact of enhanced Connexin43 expression on T lymphocyte activation and inflammatory response in
A modest blood pressure (BP) elevation results in T cell activation, which in turn promotes an inflammatory response and......
Childhood or adolescent hearing loss is often inherited as an autosomal dominant Mendelian trait,representing around......
Functional expression of gap junction gene Cx43 and the myogenic differentiation of rhabdomyosarcoma
Rhabdomyosarcoma (RD) cells express low levels of the gap junction protein connexin 43 (Cx43), and its mRNA, and display......
目的 :研究细胞间间隙连接蛋白 (connexin43,Cx43)与基因治疗中旁观者效应的关系。方法 :将不同 Cx43表达水平的中国仓鼠卵巢细胞 ......
已证明妊娠子宫肌的缝隙连接结合体是Connexin43(Cx43)。作者用间接免疫荧光法检测子宫肌层Cx43,子宫平滑肌瘤和细胞培养液中Cx_(......
Background Gap junction channels formed by connexin43 (Cx43) protein are important in cardiac morphogenesis, and Cx43 g......
The form of Charcot-Marie-Tooth (CMT) neuropathy that maps to Xql3 is X-linked dominant, or X-linked intermediate. Hete......
Neonatal sepsis is common in neonatal intensive care units,often complicated by injury to the immature brain. Previous s......
Cardiomyocyte-like differentiation of human bone marrow mesenchymal stem cells after exposure to 5-a
Objective To investigate the potential of adult mesenchymal stem cells(MSCs)derived from human bonemarrow to undergo ca......
Autologous transplantation of bone marrow mononuclear cells improved heart function after myocardial
AIM: To investigate whether autologous transplantation of adult stem cells could improve post-infarcted heart function.......
心脏缝隙连接蛋白Connexin40选择性地表达于心房细胞并介导心房的电活动的协调。作者假设原发性心房颤动(AF)有其遗传基础:GJA5(编......
Elevated Intracellular Ca~(2+) Signals by Oxidative Stress Activate Connexin 43 Hemichannels in Oste
Elevated oxidative stress(OS)during aging leads to bone loss.OS increases intracellular Ca2+([Ca2+]i),resulting in cellu......
Cx40 mRNA expression in crista terminalis and left atrium of patients with rheumatic heart disease a
Objectives:To explore possible mechanisms of connexin40(Cx40)remodeling by detecting Cx40 mRNA expression of the crista ......
Objective:To assess the effect of angiotensin II type 1(AT1)receptor antagonist losartan on myocardium con- nexin43(Cx43......
Dephosphorylation of cardiomyocyte Cx43 is associated with myocardial ischemia and reperfusion injur
Objective:Myocardial ischemia/reperfusion(I/R) injury is the leading cause of death in the world. However,the details of......
The connexin 43 (Cx43) proteins, which is the predominant protein that can form gap junctions and non-junctional hemicha......
背景:脐血间充质干细胞诱导分化为心肌细胞后移植入心肌缺血组织,可以通过与宿主细胞建立联系来修复取代缺血心肌组织。目的:对犬......
Objective:To evaluate the arrhythmogenic effects of dismantling cadherin-mediated adhesion by recombinant mouse aminopep......
In this review,we focused on two molecules,connexin and sodium-glucose cotransporter,which can link to diabetic hyperfil......
Background Stem cells have multilineage differentiation capacity,which makes bone marrow mesenchymal stem cells(BMSCs) d......
Objective: To explore the effect and mechanism of angiotensin Ⅱ receptor blockers-Irbesartan on occurrence of ventricul......
Expression of gap junction genes connexin 32 and connexin 43 mRNAs and proteins,and their role in he
AIM:To investigate the relationship betweenhepatocarcinogenesis and the expression of connexin32(cx32),connexin43(cx43)......
AIM:To investigate gap junctional intercellularcommunication (GJIC) in hepatocellular carcinoma celllines,and signal tr......
间隙连接蛋白 (Connexin,Cx)是一个构成间隙连接(Gap junction,GJ)的蛋白家族 ,大约有 2 0个成员。相邻细胞间通过间隙连接所介导......
Temporal dynamic changes of connexin 43 expression in C6 cells following lipopolysaccharide stimulat
Connexin 43, a gap junction protein, is expressed mainly in glia in the central nervous system.Neuroinflammation plays a......
Effects of all-trans-retinoic acid on the expression and tyrosine phosphorylation of gap junction co
Objective: To investigate the signal transduction mechanism of gap junctional genes connexin43 in human cervical carcino......
Objective: In this research, we studied the TGF-β1 effects on connexin-43 expression in cultured human bladder smooth m......
心房颤动(房颤)是临床上最常见的心律失常之一.房颤的具体机制至今尚未完全阐明.缝隙连接是存在于相邻细胞间的一种特殊膜蛋白通道......
糖尿病视网膜病变是糖尿病最常见的微血管并发症之一，也是一种常见的致盲性眼病。缝隙连接蛋白(connexin)介导的细胞间通信在维持视......
机体的内部平衡及脏器结构功能的稳定有赖于细胞之间及细胞与外环境的相互作用,通过粘合与信号转导对细胞表型与行为进行社会性调......
Objective:To investigatethesignaltransductionmechanismof gap junctionalgenesconnexin43in human cervicalcarcinogenesis.Me......
Objective:To investigatethesignaltransductionmechanismof gap junctionalgenesconnexin43in human cervicalcarcinogenesis.Me......
目的:构建pEGFP/缝隙连接蛋白(connexin,Cx)50真核表达载体,观察其在细胞内的表达和功能情况。方法:经PCR获得Cx50基因片段,重组至......
目的:通过建立自制量子点荧光免疫组织化学技术,对人晶状体缝隙连接蛋白(Connexin,Cx)50表达水平进行检测。方法:正常人和先天性白......
新生儿先天性听力损失是一种常见的出生缺陷。研究表明,新生儿听力损失发生率为0.1%～0.3%,重症监护病房的新生儿听力损失发生率可高......
目的鉴定在冠状动脉粥样硬化性心脏病猝死者心肌中心肌连接蛋白(connexin,CX)40、免疫及炎症相关的小分子RNA(micro155)的表达及探......
Charcot- Marie- Tooth(CMT)病是一组具有遗传异质性的末稍神经系统遗传病 ,近来人们发现 X连锁显性 Char-cot- Marie- Tooth(CMTX......
AIM:To determine the ultrastructure of junction areasbetween neurons and astrocytes of supraoptic nuclei in ratsorally ......
