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目的 建立大鼠单纯臂丛下干损伤屈指功能重建动物模型,并探讨其可行性。 方法 将60 只 SD大鼠随机分为3组:A组为单纯臂丛C8、T1 神经根撕脱造成臂丛单纯下干损伤;B组为 C7 ~T1 神经根撕脱;C组为 C8、T1神经根撕脱并将臂段正中神经造成约2 cm缺损。通过肉眼观察和肌电检测,评价造模结果。 结果 C8、T1 神经根撕脱且神经缺损组(即C组)下干神经损伤完全,而上干神经功能未受损,明显好于 A、B组。 结论 C8、T1 神经根撕脱且臂部正中神经缺损是建立大鼠单纯臂丛下干损伤屈指功能重建可行、理想的动物模型。
OBJECTIVE: To establish an animal model of flexorial function reconstruction of the inferior brachial plexus injury in rats and its feasibility. Methods Sixty Sprague-Dawley rats were randomly divided into three groups: group A was sole brachial plexus C8, root brachial plexus injury was caused by avulsion of T1 nerve root; avulsion of C7-T1 nerve root in group B; T1 nerve root avulsion and the median nerve arm caused about 2 cm defect. Through the naked eye and myoelectricity test, evaluation of modeling results. Results C8 and T1 nerve root avulsion and nerve defect group (group C), the dry nerve injury was complete, while the upper nerve function was not impaired, significantly better than the A, B group. Conclusions It is a feasible and ideal animal model for the reconstruction of C8 and T1 nerve root avulsion and central median nerve defect in rats with simple brachial plexus injury.