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目的探讨正常血压人群以及高血压人群中不同血压昼夜模式与心率变异性(HRV)的相关性分析。方法共入选2009年1月至2010年8月中山大学附属第一医院门诊及病房患者406例,其中高血压病例286例,根据动态血压监测结果分为杓型组、非杓型组和反杓型组,并设对照组120例。全部病例均在监测动态血压的同时记录动态心电图,并分析心率变异性的时域指标。结果非杓型组和反杓型组的SDNN、SDANN、SDNN index、RMSSD、pNN50和Triangular Index值均比杓型组和对照组降低(P<0.05),其中,反杓型组的上述指标明显降低。结论不同血压昼夜模式的高血压病患者HRV指标有明显差别,血压昼夜模式消失的高血压病患者自主神经功能受损更加严重。
Objective To investigate the correlation between different day-night patterns of blood pressure and heart rate variability (HRV) in normotensive and hypertensive populations. METHODS: A total of 406 outpatients and wards in the First Affiliated Hospital of Sun Yat-sen University from January 2009 to August 2010 were selected. Among them, 286 cases of hypertension were divided into dipper group, non-dipper group and anti-dipper group according to ambulatory blood pressure monitoring results Type group, and set the control group of 120 cases. All cases were recorded at the same time monitoring ambulatory blood pressure electrocardiogram, and analyze the time-domain index of heart rate variability. Results SDNN, SDANN, SDNN index, RMSSD, pNN50 and Triangular Index of non-dipper group and anti-dipper group were lower than those of dipper group and control group (P <0.05) reduce. Conclusion There are significant differences in HRV indexes between patients with different blood pressure diurnal patterns of hypertension and those with hypertensive patients whose blood pressure diurnal patterns disappear are more impaired.