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AIM:Endoplasmic reticulum stress(ERS)may contribute to the pathogenesis of myocardial reperfusion injury.The purpose ofthis study was to investigate the detailed time course of ERS induction and to test if resveratrol prevents reperfusion injury through inhibition of ERS upon reperfusion.METHODS:Isolated rat hearts were perfused on a Langendorff apparatus and subjected to 30 min of
AIM: Endoplasmic reticulum stress (ERS) may contribute to the pathogenesis of myocardial reperfusion injury. The purpose of this study was to investigate the detailed time course of ERS induction and to test if resveratrol prevents reperfusion injury through inhibition of ERS upon reperfusion. METHODS: Isolated rat hearts were perfused on a Langendorff apparatus and subjected to 30 min of