慢性萎缩性胃炎是临床常见的胃部疾病,由于其与胃癌尤其是肠型胃癌的发生呈显著正相关,1978年世界卫生组织将其定为癌前病变[1]。我们以人类饮食中不可缺少的二大因素—食物的热度与咸度,创建了快速建立慢性萎缩性胃炎动物模型的方法,并观察从正常胃黏膜发展到萎缩性胃炎的演变 Chronic atrophic gastritis is a common clinical gastric disease, due to its significant positive correlation with the occurrence of gastric cancer, especially intestinal type gastric cancer, which was defined as a precancerous lesion by the World Health Organization in 1978 [1]. We established the rapid establishment of an animal model of chronic atrophic gastritis based on the heat and saltiness of food, the two most important factors in human diet, and observed the evolution from normal gastric mucosa to atrophic gastritis