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目的探讨分析老年2型糖尿病伴高血压患者血清25羟维生素D的变化及临床意义。方法老年2型糖尿病伴高血压100例患者的临床病例资料,将其作为观察组,另外随机选择100例无糖尿病病史的患者作为正常对照组,对比分析两组患者的常规生化指标、血清25(OH)D3水平。结果老年2型糖尿病伴高血压的观察组患者的血清25(OH)D3水平明显低于无糖尿病病史的正常对照组,两组间差异具有统计学意义(P<0.05)。结论老年2型糖尿病伴高血压患者血清25羟维生素D水平明显降低,二者呈负相关关系,血清25羟维生素D水平降低可增加糖尿病高血压病变的风险。
Objective To investigate the changes and clinical significance of serum 25-hydroxyvitamin D in elderly patients with type 2 diabetes mellitus and hypertension. Methods A total of 100 elderly patients with type 2 diabetes mellitus and hypertension were enrolled as observation group. Another 100 patients without diabetes mellitus were randomly selected as normal control group. The biochemical parameters, serum 25 OH) D3 level. Results The level of serum 25 (OH) D3 in the observation group with type 2 diabetes mellitus and elderly with hypertension was significantly lower than that of the normal control group without a history of diabetes mellitus (P <0.05). Conclusions Serum 25-hydroxyvitamin D levels in elderly patients with type 2 diabetes mellitus and type 2 diabetes mellitus were significantly lower than those in patients with type 2 diabetes mellitus. There was a negative correlation between serum 25-hydroxyvitamin D levels and serum 25-hydroxyvitamin D levels in diabetic hypertensive patients.