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目的探讨在阴道炎诊断中联合检测六项白带生化标志物的临床意义。方法妇产科450例患者白带标本,采用试剂盒联合检测N-乙酰-β-D氨基葡萄糖苷酶、脯氨酸氨基肽酶、唾液酸苷酶、白细胞酯酶、过氧化氢(H2O2)、pH值等六项指标,对检测结果进行分析比较。结果 95例N-乙酰-β-D氨基葡萄糖苷酶呈弱阳或阳性,其中14例>4.8,占14.7%;81例pH≤4.6,约占85.3%。135例脯氨酸氨基肽酶或(和)唾液酸苷酶呈阳性,315例全阴性。280例白细胞酯酶阴性,170例阳性。290例H2O2呈阴性或弱阳性,160例呈阳性。240例pH值在4.0~4.5之间,210例>4.5。结论联合检测白带生化标志物,对辅助诊断女性阴道疾病具有重要的应用价值,可广泛应用于临床。
Objective To investigate the clinical significance of the combined detection of six leucorrhea biochemical markers in the diagnosis of vaginitis. Methods The leucorrhea specimens from 450 obstetrics and gynecology patients were tested for the presence of N-acetyl-β-D-glucosaminidase, proline aminopeptidase, neuraminidase, leukocyte esterase, hydrogen peroxide (H2O2) pH and other six indicators, the test results were analyzed and compared. Results 95 cases of N-acetyl-β-D glucosaminidase were weak positive or positive, of which 14 cases> 4.8, accounting for 14.7%; 81 cases pH ≤ 4.6, accounting for 85.3%. 135 cases of proline aminopeptidase or (and) neuraminidase were positive, 315 cases were all negative. 280 cases of leukocyte esterase negative, 170 cases were positive. 290 cases of H2O2 was negative or weak positive, 160 cases were positive. 240 cases of pH between 4.0 to 4.5, 210 cases> 4.5. Conclusions The combined detection of leucorrhea biochemical markers has an important value in the diagnosis of vaginal diseases in women and can be widely used in clinic.