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测定３８例肾脏病人尿液的ｐＨ值、可滴定酸（ＴＡ）、铵离子（ＮＨ４＋），同时测定内生肌酐清除率（Ｃｃｒ），并按Ｃｃｒ进行分组。结果发现慢性肾功能不全（ＣＲＦ）病人尿ＴＡ、ＮＨ４＋均明显下降，泌ＮＨ４＋功能与Ｃｃｒ减退状况平行。
The urinary pH, titratable acidity (TA) and ammonium ion (NH4 +) were measured in 38 cases of renal patients. The creatinine clearance rate (Ccr) was measured simultaneously and grouped according to Ccr. The results found that patients with chronic renal insufficiency (CRF) urinary TA, NH4 were significantly decreased secretion of NH4 + function and Ccr decline in parallel.