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目的探讨原发性胆囊癌与临床病理特征的关系。方法对31例经术后病理证实的原发性胆囊癌患者的病理和随访资料进行回顾性分析。结果77%的患者有明确的胆囊炎、胆结石病史,最常见的症状为腹痛,其次为黄疸和右上腹包块,统计学分析显示肿瘤的病理分期、分化程度、淋巴转移、浸润程度与预后显著相关。结论重视胆囊癌的早期诊断,可望改善其预后,Nevin分期、分化程度是原发性胆囊癌有意义的独立预后因子。
Objective To investigate the relationship between primary gallbladder cancer and clinicopathological features. Methods The pathology and follow-up data of 31 patients with primary gallbladder carcinoma proved by pathology were retrospectively analyzed. Results 77% of the patients had definite cholecystitis and gallstones history. The most common symptom was abdominal pain, followed by jaundice and right upper quadrant. The statistical analysis showed that the pathological stage, differentiation, lymphatic metastasis, degree of infiltration and prognosis Significant correlation. Conclusion The importance of early diagnosis of gallbladder cancer is expected to improve its prognosis, Nevin stage, degree of differentiation is a significant independent prognostic factor for primary gallbladder cancer.