缺血性心脏病是世界上具有最高发病率和死亡率的疾病。近十余年来,利用血管发生治疗缺血性心脏病日益受到人们的重视。1　治疗性血管发生的基本原理　　血管受到局部缺氧、缺血、机械牵拉及炎症等刺激后,已分化成熟的内皮细胞被激活,局部血管舒张,血管通透性增加,血管外纤维蛋 Ischemic heart disease is the world’s disease with the highest morbidity and mortality. In recent ten years, the use of angiogenesis in the treatment of ischemic heart disease has drawn increasing attention. The basic principles of therapeutic angiogenesis Vascular by local hypoxia, ischemia, mechanical traction and inflammation and other stimuli, have been differentiated mature endothelial cells are activated, local vasodilation, increased vascular permeability, extravascular fibrin