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目的 测定冠心病心绞痛患者血浆C -反应蛋白 (CRP)水平 ,探讨CRP与冠心病 (CHD)病变程度的关系 ,为指导冠心病心绞痛临床治疗和预防提供依据。方法 测定 1 7例不稳定型心绞痛 (UA)者、2 0例稳定型心绞痛 (SA)和 1 9例对照者血浆CRP含量。结果 血浆CRP水平UA组明显高于SA组和对照组 ,有显著性差异 (P <0 .0 1 ) ,SA组和对照组相比 ,亦有显著性差异 (P <0 .0 5 )。血浆CRP水平在对照组、稳定型心绞痛组、不稳定型心绞痛组依次增高。结论 提示CRP浓度与冠心病的发生、发展及严重程度有明确相关性。
Objective To determine the level of plasma C - reactive protein (CRP) in patients with coronary heart disease (CHD) and to investigate the relationship between CRP and the severity of coronary heart disease (CHD), so as to provide evidence for clinical treatment and prevention of angina pectoris. Methods The plasma levels of CRP in 17 patients with unstable angina pectoris (UA), 20 patients with stable angina (SA) and 19 controls were measured. Results Plasma CRP level in UA group was significantly higher than that in SA group and control group (P <0.01). There was also significant difference between SA group and control group (P <0.05). Plasma CRP levels increased in the control group, stable angina pectoris group and unstable angina pectoris group. Conclusions CRP concentration and coronary heart disease occurrence, development and severity of a clear correlation.