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目的 观察由红细胞葡萄糖-6-磷酸脱氢酶缺陷(G-6-PD)所致新生儿黄疸治疗时，静脉注射丙种球蛋白(IVIG)的退黄效果。方法 31例G-6-PD缺陷新生儿黄疸中12例对照组用常规治疗，19例治疗组除常规治疗外加用IVIG每日0.4～1.0 g/kg。用经皮胆红素测定仪监测治疗疗效。结果 在治疗24和48 h后与治疗前对比，治疗组的退黄效果和对照组比较差异有显著性意义(P<0.001)。结论 加用IVIG治疗因G-6-PD缺陷致新生儿黄疸有效。
Objective To observe the antipyretic effect of intravenous gamma globulin (IVIG) in neonatal jaundice caused by G-6-PD of erythrocyte glucose-6-phosphate dehydrogenase. Methods Thirty-one neonates with G-6-PD deficient jaundice in the control group were treated with conventional therapy, and 19 patients in the treatment group were treated with IVIG 0.4-1.0 g / kg daily. Transdermal bilirubin meter to monitor treatment efficacy. Results At 24 and 48 h after treatment, compared with before treatment, the treatment group had significant difference (P <0.001) in the anti-yellowing effect compared with the control group. Conclusions Adding IVIG is effective in neonatal jaundice due to G-6-PD deficiency.