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一、治疗慢性支气管炎:现已证实引起咳嗽的机制中。副交感神经活动亢进参与。因654-2能对抗副交感传导介质乙酰胆碱,故可阻断异常咳嗽冲动的传导。笔者以莨菪类药伍用扑尔敏及适当抗感染药治疗上百例急慢支引起的顽咳、久咳,总有效率达94%,较优于其它治疗方法。二、治疗肺心病:此药能解除机体缺氧所致的血管痉挛。除低肺组织郁血,减少心脏前后负荷,增加肺有效循环血量,提高血氧浓度;此外,尚能解除支气管痉挛,减少腺液分泌,从而使肺的通气功能得到改善,口服或肌注法应由首日量30mg,逐日递增至第5日90mg以上,均分2~3次用药。静滴法可用40~80mg加入10%葡萄糖中,日1次,7~10日为一疗程。三、治疗急性肾小球肾炎:因其能解除肾小球微血管痉挛,解除乙酰胆碱蓄积所致的免疫亢进,抑制粒细胞聚集,改善肾功能,可每次1mg/kg,每日2~3次肌注或口服。
First, the treatment of chronic bronchitis: Has been proven to cause cough in the mechanism. Parasympathetic activity hyperthyroidism involved. Because 654-2 can antagonize the parasympathetic mediator acetylcholine, it can block the abnormal cough impulse conduction. The author of quinqueflavine drug chlorpheniramine and appropriate anti-infectives treatment of hundreds of cases of acute and chronic bronchitis caused by stubborn cough, chronic cough, the total effective rate of 94%, better than other treatments. Second, the treatment of pulmonary heart disease: the drug can relieve the body caused by hypoxia vasospasm. In addition to low blood flow in the lung tissue, reduce the heart before and after the load and increase the effective circulating blood volume of the lungs to improve blood oxygen concentration; In addition, still able to relieve bronchial spasm, reduce the secretion of glandular fluid, so that lung ventilation improved, oral or intramuscular Law should be the first day of the amount of 30mg, day by day increased to 90mg more than the 5th, were divided into 2 or 3 times medication. Intravenous infusion method available 40 ~ 80mg added 10% glucose, day 1, 7 to 10 for a course of treatment. Third, the treatment of acute glomerulonephritis: Because of its ability to relieve glomerular capillary vasospasm, the lifting of the immune hyperthyroidism caused by accumulation of acetylcholine, inhibit granulocyte aggregation, improve renal function, each 1mg / kg, 2 to 3 times a day Intramuscular or oral.