我院1984年1月至1990年12月收治重度经口有机磷中毒患者243例,36例(15.22%)并发脑水肿患者均有不同程度的阿托品临床效应“低下”。本文总结分析临床资料,初步探讨其发生机制,供同道们参考。临床资料一,一般情况:性别:男12例,女24例。年龄:18～43岁,均系重度口服有机磷农药中毒。其中滴滴畏(D.D.V.P)13例,口服20～80毫升;对硫磷(1605)12例,口服30～50毫升;乐果11例,口服50毫 Our hospital from January 1984 to December 1990 were treated severe oral organophosphate poisoning in 243 patients, 36 patients (15.22%) with cerebral edema patients have varying degrees of clinical effect of atropine “low.” This article summarizes and analyzes the clinical data, and initially explores the mechanism of its occurrence for the reference of fellow. Clinical data First, the general situation: Sex: 12 males and 24 females. Age: 18 ~ 43 years old, are heavily oral organophosphorus pesticide poisoning. Among them, 13 cases of D.D.V.P were orally administered with 20-80 ml; parathion 1605 12 cases were orally administered with 30-50 ml omethoate and 50 cases were orally administered orally