论文部分内容阅读
目的分析肾病综合征(NS)患儿对糖皮质激素短期应用的转归情况。方法回顾南京军区南京总医院原发性肾病综合征1 116例住院患儿,分析临床分型和糖皮质激素应用4周的疗效。结果单纯型NS所占比例在MCNS(轻微病变)中最大;激素应用4周后完全缓解率以MCNS最高,其次为MsPGN(系膜增生性肾小球肾炎)。结论肾病综合征患儿的临床表现、肾组织病理和应用糖皮质激素4周后转归情况存在相关性。
Objective To analyze the outcome of short-term glucocorticoid use in children with nephrotic syndrome (NS). Methods A total of 1 116 inpatients with primary nephrotic syndrome in Nanjing General Hospital of Nanjing Military Region were retrospectively analyzed. The clinical effects and clinical efficacy of glucocorticoid for 4 weeks were analyzed. Results The proportion of simple NS was the largest in MCNS (slight lesion). The complete remission rate was highest in MCNS after 4 weeks of hormone application, followed by MsPGN (mesangial proliferative glomerulonephritis). Conclusion The clinical manifestations of nephrotic syndrome in children, renal pathology and the application of glucocorticoid after 4 weeks of the situation there is a correlation.