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1970年~1973年,作者在美国圣安东尼奥先后应用青霉素、红霉素和克林达霉素治疗白喉带菌者,比较其疗效。 对确诊白喉患者的家属及密切接触者作鼻咽培养,无症状但培养出产毒白喉杆菌者为观察对象。带菌者大多数在家隔离,并按下列三种方案之一进行治疗。 1、苄星霉素:肌肉注射。1~5岁:60万单位、5岁以上:120万单位。 2、红霉素:口服。体重为22公斤以下者:250毫克、每日2次×7天,22~45公斤者:250毫克、每日3次×7天,45公斤
From 1970 to 1973, the author used penicillin, erythromycin and clindamycin successively to treat diphtheria carriers in San Antonio, USA, and compared their efficacy. Diphtheria of patients diagnosed with family members and close contact for nasopharyngeal culture, asymptomatic but the production of drug-producing diphtheria bacillus were observed. Carriers are mostly isolated at home and treated according to one of three options. 1, Benzathine: intramuscular injection. 1 to 5 years old: 600,000 units, 5 years old and above: 1.2 million units. 2, erythromycin: oral. Weight 22 kg or less: 250 mg, 2 times a day × 7 days, 22 ~ 45 kg were: 250 mg, 3 times a day × 7 days, 45 kg