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有研究证明,用H_2受体拮抗剂治疗2个月后大约85%的十二指肠溃疡可治愈,但停药一年的复发率可达85%.即使夜间维持用药,一年内的复发率也可达23~37%.对于停药或剂量减少后溃疡反复发作的患者,近端胃迷走神经切断术是有效而安全的.Stoddard等报告对有症状的溃疡,迷切的治愈率为91%(平均随访6.5年),迷切加胃窦切除则可达99%(随访16年),但副作用较大.近端迷切对幽门和幽门前溃疡的疗效不佳.
Studies have shown that about 85% of duodenal ulcers can be cured after 2 months of treatment with H 2 receptor antagonists, but the relapse rate of up to 85% in one year of withdrawal Even if the drug is maintained at night, the recurrence rate in one year Also up to 23 to 37% .For patients with recurrent or discontinued ulcer after discontinuation or dose reduction, proximal gastric vagotomy is effective and safe.Stoddard et al reported on the symptoms of ulcers, the cure rate of cesarean section was 91% (Mean follow-up of 6.5 years), while the excision of gastric anastomosis can reach 99% (follow-up of 16 years), but the side effects are greater.Most proximal pyloric pyloric and pyloric ulcer efficacy is not good.