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遗传性疾病是一类常见病,在群体中的发病率达1～3％,对人类危害极大,是医学上长期渴望解决的一个难题。而出生前诊断和防治却是解决这一难题的一种有效措施。遗传病的产前诊断遗传病大多数是先天的,终生的,而且在出生前已存在,故可在产前诊断出来。一、概况近二十年来,先天畸形和遗传病的产前诊断研究发展很快。1959年Lejeune氏发现了先天愚型的染色体畸变,几年后即提出作产前诊断的建议。1965年Klinger氏首次应用培养的羊水细胞进行胎儿的染色体分析。1967年Steel氏作了第一例染色
Hereditary diseases are a common type of disease with a prevalence of 1 to 3% in the population, which is extremely harmful to human beings and is a difficult problem that medicine longs to solve. Prenatal diagnosis and prevention is an effective measure to solve this problem. Prenatal diagnosis of genetic diseases Inherited diseases are mostly congenital, lifelong and pre-existing, so they can be diagnosed prenatal. First, the profile Nearly two decades, congenital malformations and genetic diseases prenatal diagnosis of rapid development. In 1959 Lejeune’s discovery of the idiotypic chromosome aberrations, proposed a few years later for prenatal diagnosis. 1965 Klinger’s first application of cultured amniotic fluid cells for fetal chromosomal analysis. Steel made the first case of staining in 1967