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本研究的目的在于观察国产醋氨己酸锌在消化性溃疡病治疗中的作用及其安全性。对２１９例经胃镜证实的消化性溃疡，其中胃溃疡６１例，十二指肠溃疡１５８例，两组溃疡病人分别接受按双盲双模拟随机编码的药物治疗。试验药物醋氨己酸锌，剂量为９００ｍｇ／ｄ，对照药西米替丁为１ｇ／ｄ。研究结果：胃溃疡６周溃疡愈合率醋氨己酸锌组为５４．２％（对照５６．７％，ｐ＞０．０５），十二指肠溃疡４周溃疡愈合率分别为５５．８％和５１．９％（Ｐ＞０．０５）。两种药物在治疗中未发现明显药物不良反应，研究结果表明：醋氨己酸锌治疗消化性溃疡病的效果与西米替丁相似，而且无明显药物不良反应。
The purpose of this study is to observe the role and safety of domestic zinc acetylcarnoate in the treatment of peptic ulcer disease. 219 cases of peptic ulcer confirmed by gastroscopy, including 61 cases of gastric ulcer, 158 cases of duodenal ulcer, ulcer patients were treated by double-blind random double-coded drug treatment. Test drug zinc acetohexamide, a dose of 900mg / d, control drug cimetidine 1g / d. Results: The healing rate of ulcer in 6-week gastric ulcer patients was 54.2% (56.7%, p> 0.05), and the healing rates of 4-week ulcer patients in duodenal ulcer were 55.8 % And 51.9% (P> 0.05). The two drugs in the treatment of significant adverse drug reactions were not found, the results show that: the efficacy of zinc acetate vinegar acid in the treatment of peptic ulcer disease and cimetidine similar, but no obvious adverse drug reactions.