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神经营养素(neurotrophin)家族是近几年发现的神经营养因子基因家族。目前已知的成员除神经生长因子外,还有脑源性神经营养因子、神经营养素-3、神经营养素-4。本文综述了其基因克隆与结构特征、基因表达与调控、生物学功能等方面的研究进展。
The neurotrophin family is a family of neurotrophin genes found in recent years. Known members in addition to nerve growth factor, there are brain-derived neurotrophic factor, neurotrophin-3, neurotrophin-4. This review summarizes the recent advances in gene cloning and structural features, gene expression and regulation, and biological functions.