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目的评价伊曲康唑治疗RICU中IFI的效果及不良反应。方法回顾性分析了26例RICU中诊断IFI的患者的病历资料,观察疗效及不良反应。结果总有效率73.08%(19/26)。确诊病例有效率100%(3/3),临床诊断病例有效率73.68%(14/19),拟诊病例50.00%(2/4)。不良反应发生率7.69%(2/26)。1例发生心力衰竭,停药后症状消失。结论伊曲康唑治疗RICU中侵袭性肺真菌病效果确切、安全,慎用于冠心病患者。
Objective To evaluate the efficacy and adverse effects of itraconazole in the treatment of IFI in RICU. Methods A retrospective analysis of 26 cases of RICU in the diagnosis of IFI in patients with medical records, to observe the efficacy and adverse reactions. The total effective rate was 73.08% (19/26). The diagnosed cases were 100% (3/3), 73.68% (14/19) clinically diagnosed cases and 50.00% (2/4) cases were diagnosed clinically. The incidence of adverse reactions was 7.69% (2/26). 1 case of heart failure, symptoms disappeared after stopping. Conclusions Itraconazole is effective and safe in the treatment of invasive pulmonary mycoses in RICU and is used with caution in patients with coronary heart disease.