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目的:观察布地奈德混悬液(普米克令舒)阶梯雾化吸入辅助治疗小儿急性感染性喉炎的疗效。方法:将100例小儿急性感染性喉炎患儿按随机数字表法分为观察组52例和对照组48例,两组均给予相同综合治疗包括对症治疗、抗感染、抗炎等,同时加用布地奈德混悬液,≤1岁每次0.5 mg,>1岁每次1 mg,加生理盐水至3 mL雾化吸入:对照组给予常规雾化治疗,即2次/日;观察组给予阶梯雾化治疗,即0、20、40 min各雾化吸入一次,之后每8 h一次,第2天改为常规雾化。两组患儿均治疗至症状体征完全消失(治愈)后出院,治疗期间对两组进行相同的护理。观察用药后患儿症状体征改善情况,并于治疗24 h后比较两组疗效。结果:总有效率观察组100.0%,对照组95.8%,两组比较差异无统计学意义(P>0.05);平均住院时间观察组3.7 d,对照组5.3 d,两组比较差异有统计学意义(P<0.05)。结论:急性感染性喉炎患儿在对症治疗、抗感染、抗炎等综合治疗同时,加用布地奈德混悬液阶梯雾化辅助治疗并给予正确的护理指导,可缩短住院时间,安全有效。
Objective: To observe the effect of budesonide suspension (pulmicort respirator) step-atomization inhalation in the treatment of acute infection laryngitis in children. Methods: A total of 100 children with acute respiratory laryngitis were divided into observation group (n = 52) and control group (n = 48) by random number table. Both groups were given the same comprehensive treatment including symptomatic treatment, anti-infection and anti- With budesonide suspension, ≤ 1-year-old 0.5 mg each,> 1-year-old each 1 mg, plus saline to 3 mL inhalation: the control group given conventional aerosol treatment, that is, 2 times / day; Atomized inhalation was given at 0, 20, and 40 min, once every 8 hours, and changed to conventional aerosolization on the second day. Both groups of children were treated until symptoms and signs disappeared completely (cured) and discharged. During the treatment, the two groups were given the same care. Observed after treatment of children with symptoms and signs of improvement, and in the treatment of 24 h after the two groups were compared. Results: The total effective rate was 100.0% in the observation group and 95.8% in the control group, with no significant difference between the two groups (P> 0.05). The average length of stay in the observation group was 3.7 days and that in the control group was 5.3 days. There was significant difference between the two groups (P <0.05). CONCLUSIONS: In children with acute infectious laryngitis, simultaneous treatment with symptomatic treatment, anti-infection, anti-inflammatory and other adjunctive therapy with budesonide suspension step-by-step nebulization and proper nursing guidance can shorten the hospital stay and be safe and effective .