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目的观察硝普钠联合小剂量多巴胺治疗肺源性心脏病心力衰竭的疗效。方法 99例肺源性心脏病心力衰竭患者,依据治疗方法不同分为观察组(76例)和对照组(23例),两组均给予小剂量多巴胺治疗,观察组加用硝普钠治疗。比较两组临床疗效、肺动脉压、右心室内径及不良反应。结果观察组总有效率为92.11%(70/76),对照组总有效率为69.57%(16/23),观察组总有效率高于对照组,差异具有统计学意义(P<0.05);观察组治疗后肺动脉压和右心室内径低于对照组,差异具有统计学意义(P<0.05);两组不良反应发生率比较差异无统计学意义(P>0.05)。结论硝普钠联合小剂量多巴胺治疗肺源性心脏病心力衰竭可显著提高患者心功能,改善患者临床体征和症状,具有较高的实用价值和推广价值,值得推广应用。
Objective To observe the curative effect of sodium nitroprusside and low dose dopamine on heart failure of patients with pulmonary heart disease. Methods Ninety-nine patients with heart failure of pulmonary heart disease were divided into observation group (76 cases) and control group (23 cases) according to different treatment methods. Both groups were given low-dose dopamine treatment and observation group were treated with sodium nitroprusside. The clinical efficacy, pulmonary arterial pressure, right ventricular diameter and adverse reactions were compared between the two groups. Results The total effective rate was 92.11% (70/76) in the observation group and 69.57% (16/23) in the control group. The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). The pulmonary arterial pressure and the right ventricular diameter were lower in the observation group after treatment than those in the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Sodium nitroprusside combined with low-dose dopamine in the treatment of heart failure of pulmonary heart disease can significantly improve the cardiac function and improve the clinical signs and symptoms of patients with high practical value and promotion value, which is worth popularizing and applying.