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The relative frequency of depression in people with primary progressive multip le sclerosis (PPMS) (30 patients) compared with those with a history of relapse (106 patients) was determined.Three participants in the progressive group and 28 in the relapsing group had a lifetime history of major depression.The lifetime morbidity ratio for major depression in relapsing patients was 2.64 compared wit h that of PPMS.
The relative frequency of depression in people with primary progressive multip le sclerosis (PPMS) (30 patients) compared with those with a history of relapse (106 patients) was determined. Participants in the progressive group and 28 in the relapsing group had a lifetime history of major depression. The lifetime morbidity ratio for major depression in relapsing patients was 2.64 compared wit h that of PPMS.