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采用电子束熔化(EBM)成形工艺,制造具有可控多孔结构的Ti6Al4V植入体,分析测试其微观孔隙结构特征、孔隙率以及力学性能。扫描电镜观测结果表明,所制备的钛合金植入体孔隙结构特征与设计结构相符合,证明EBM技术能够实现钛合金植入体孔隙结构的控制;测得多孔植入体的孔隙率为60.1%,相应的抗压强度为163MPa,弹性模量为14GPa,与人体骨组织弹性模量相近。利用改进的碱热处理方法进行表面改性,并浸泡在模拟体液中以诱导磷灰石的形成。体外细胞培养试验结果表明,培养7d后成骨细胞在改性的试件表面大量粘附、生长、增殖。
Ti6Al4V implants with controllable porous structure were fabricated by electron beam melting (EBM) forming process. Their microscopic pore structure, porosity and mechanical properties were analyzed. Scanning electron microscopy results showed that the pore structure of the prepared titanium alloy implant was consistent with the designed structure, which proves that EBM can control the pore structure of titanium alloy implant. The porosity of the porous implant is 60.1% , The corresponding compressive strength of 163MPa, elastic modulus of 14GPa, similar to human body tissue elastic modulus. Surface modification is performed using an improved alkali heat treatment and immersed in simulated body fluids to induce the formation of apatite. The results of in vitro cell culture showed that after cultured for 7 days, osteoblasts could adhere to, grow and proliferate on the surface of modified specimens.