着色性干皮病(XP)是一种乳幼儿期发病的常染色体遗传病,主要症状为高度日光过敏性皮炎,皮肤癌的发生率高。本病首先由Kaposi(1874)报告,目前可分A～G 7组及8个变型,并证实本病有紫外线特异性内切核酸酶的缺乏。A、D、G组患者除特征性皮肤症状外,可并有神经症状,A组患者尚可并有低身长及性腺机能不全等内分泌障碍。作者指 Chromic xeroderma (XP) is an autosomal genetic disease that affects infants and young children. The main symptom is high sunlight allergic dermatitis, which is associated with a high incidence of skin cancer. The disease was first reported by Kaposi (1874) and is currently subdivided into groups A to G 7 and eight variants, confirming the absence of UV-specific endonucleases. Patients in groups A, D and G had neurological symptoms in addition to the characteristic dermatological symptoms. Patients in group A could still have endocrine disorders such as low-grade and hypogonadism. Author