论文部分内容阅读
目的探讨急性心肌梗塞（ＡＭＩ）患者血清肌钙蛋白Ｉ（ＣＴｎⅠ）含量变化的临床意义。方法对３２例急性心肌梗塞患者和３６例健康对照者血清中肌特异性肌钙蛋白Ｉ和磷酸肌酸激酶（ＣＫ－ＭＢ同功酶）活性进行检测，并分析其与ＡＭＩ临床特征的关系。结果所有３６例健康对照者血清ＣＴｎⅠ均为阴性；３２例急性心肌梗塞患者中２８例ＣＴｎⅠ阳性，２５例ＣＫ－ＭＢ阳性。结论ＣＴｎⅠ是一个特异、敏感的反映心肌损伤的血清标记物。
Objective To investigate the clinical significance of the change of serum troponin I (CTnⅠ) in patients with acute myocardial infarction (AMI). Methods Serum specific troponin I and creatine phosphokinase (CK-MB isoenzyme) activity in 32 patients with acute myocardial infarction and 36 healthy controls were measured and their relationship with clinical features of AMI was analyzed. Results Serum CTnⅠ was negative in all 36 healthy controls; CTnⅠ was positive in 28 cases and CK-MB was positive in 25 cases in 32 cases of acute myocardial infarction. Conclusion CTn Ⅰ is a specific and sensitive serum marker that reflects myocardial injury.