对美尼尔氏病患者的随访越久,发现双耳患病率越高。症状出现后2年的早期阶段,双耳发病率约15％,而20年以上者,双耳发病可超过40％,甚至高达60％。作者发现在儿童期或少年期始发的典型患者易致双耳发病。对继发耳受损的治疗学寓义是明显的。对初发耳的手术治疗应避免医源性耳聋,即使仍适应做破坏性手术也应尽可能地推迟。作者曾提出耳蜗电图和甘油试验对美尼尔氏病的预测价值。内淋巴积水的患耳常出现异常的AP/SP, The longer the follow-up of patients with Meniere’s disease, the higher the prevalence of binaural. The incidence of binaural diseases is about 15% in the early stages of 2 years after the onset of symptoms, and the incidence of binaural disorders can exceed 40% or even up to 60% for more than 20 years. The authors found that typical patients who develop in childhood or adolescence are prone to cause both ears. The therapeutic implications of secondary ear damage are obvious. Surgical treatment of primary ear should avoid iatrogenic deafness, even if it is still adapted to do destructive surgery should be delayed as much as possible. The authors have proposed the predictive value of cochlear electrograms and glycerol test for Meniere’s disease. Patients with endolymphatic hydrops often appear abnormal AP / SP,