校正后QT间期(QTc)延长与心血管疾病并发症和死亡风险增加有关已为公认,但关于其与脑卒中风险间关系尚罕有报道,且结论亦远未统一。现就基线QTc延长与继后新发脑卒中风险间关系进行大样本长程调查分析。受检对象为27 411例中年个体,基线年龄均≥45岁,且先前均无脑卒中相关临床佐证。研究中均于基线接受心电图检测,用以测算各自基线的校正心率后的QTc,若男性≥450 ms, Corrected QT interval (QTc) prolongation is associated with increased cardiovascular complications and increased risk of death, but its association with the risk of stroke is rarely reported and the conclusions are far from uniform. A large sample long-term survey analysis is now conducted on the relationship between baseline QTc prolongation and subsequent new stroke risk. Subjects were 27,411 middle-aged individuals, all with a mean age of 45 years or older, and had no prior clinical evidence of stroke. In the study, baseline ECG was used to measure the baseline QTc after correction of heart rate. If the male was ≥450 ms,