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有很大比例的供血者可检测到HGV RNA序列。这些HGV RNA阳性的供血者仅表现为轻度的ALT的增高,至少50%没有任何肝病证据。此研究目的为评估慢性肝病患者中HGV感染的患病率及其意义。 方法与结果:对554例慢性肝病患者和连续200名首次献血者进行研究。HGV RNA阳性在献血者中占3%。179例慢性丙型肝炎患者有ALT持续增高,肝组织学存在慢性炎症,抗HCV抗体和HCV RNA阳性,其中6.7%HGV
A large percentage of donors can detect HGV RNA sequences. These HGV RNA-positive donors showed only mild increases in ALT and at least 50% did not have any evidence of liver disease. The purpose of this study was to assess the prevalence and significance of HGV infection in patients with chronic liver disease. Methods and Results: 554 patients with chronic liver disease and 200 consecutive first-time donors were studied. HGV RNA positive is 3% of blood donors. 179 cases of chronic hepatitis C patients with ALT continued to increase liver histology chronic inflammation, anti-HCV antibodies and HCV RNA positive, of which 6.7% HGV