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紫癜性肾炎是儿童最常见的继发性肾小球疾病,其肾小球病变程度各病例间差异很大,临床表现很大程度上由肾小球病理变化所决定。近年来,除了对形态学改变的研究外,对本病肾小球超微结构改变的研究也越来越深入。本文根据近年国外文献资料,重点综述了紫癜性肾炎肾小球基底膜、系膜等在普通电镜及免疫电镜下的表现,同时,对超微结构改变与临床表现及其预后的关系加以讨论。
Purpura nephritis is the most common secondary glomerular disease in children, the glomerular lesions vary greatly between the various cases, the clinical manifestations largely determined by glomerular pathological changes. In recent years, in addition to morphological changes in the study of the disease glomerular ultrastructure changes more and more in-depth. Based on the foreign literature in recent years, this review focuses on the manifestations of glomerular basement membrane and mesangium in patients with purpura nephritis under ordinary electron microscopy and immunoelectron microscopy, and discusses the relationship between ultrastructural changes and clinical manifestations and prognosis.