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目的 :通过对 30例老年急性白血病患者的研究 ,了解老年急性白血病的临床特征与化疗效果及预后的关系。方法 :选择自 1998年 7月～ 2 0 0 0年 6月收治的 30例老年急性白血病 (AL)患者 ,AML 采用 DA/ HA方案 ;AL L采用 VCAP/ VCDP方案 ;AML L采用髓淋兼顾的 VCAAP方案。结果 :完全缓解者 14例 (4 6 .6 % ) ,部分缓解 3例 ,总有效率为 5 6 .6 % ,3例治疗无效 ,死于并发症。结论 :老年 AL 患者发病时临床表现重 ,病情复杂 ,心、肝、肾、骨髓等功能均差 ,对化疗药物耐受性差 ,易产生耐药 ,缓解率低 ,时间长 ,复发率、死亡率高。
OBJECTIVE: To investigate the relationship between the clinical features of elderly acute leukemia and chemotherapy efficacy and prognosis through the study of 30 elderly patients with acute leukemia. Methods: 30 elderly patients with acute leukemia (AL) who were admitted to our hospital from July 1998 to June 2000 were enrolled in this study. AML was given DA / HA, ALL was VCAP / VCDP, AML was VCAAP program. Results: Complete remission in 14 cases (46.6%), partial remission in 3 cases, the total effective rate was 56.6%, 3 cases of treatment ineffective, died of complications. Conclusion: Alzheimer’s disease patients with severe clinical manifestations, complex disease, heart, liver, kidney, bone marrow and other functions are poor, poor tolerance to chemotherapy drugs, drug resistance, low response rate, long duration, relapse rate, mortality high.