采用有机溶剂对杜仲叶中绿原酸进行浸提,用高效液相色谱法对绿原酸进行定性定量分析,考察了液固比、乙醇浓度、温度和时间对绿原酸浸出率的影响,并对绿原酸浸出过程进行了动力学模拟.结果表明,绿原酸浸出的最优条件为乙醇浓度60%(?),液固比10 m L/g,在60℃下提取40 min,该条件下绿原酸的浸出率达90.21%.乙醇浸提杜仲叶中绿原酸符合内扩散动力学模型,表观活化能Ea=11.46 k J/mol. The organic solvent was used to extract the chlorogenic acid in Eucommia leaf, and the qualitative and quantitative analysis of chlorogenic acid was carried out by high performance liquid chromatography (HPLC). The effects of liquid-solid ratio, ethanol concentration, temperature and time on chlorogenic acid leaching rate were investigated. The results showed that the optimum conditions for the leaching of chlorogenic acid were ethanol concentration 60% (?), Liquid-solid ratio 10 m L / g, extraction at 60 ℃ for 40 min, Under these conditions, the leaching rate of chlorogenic acid was 90.21%. The chlorogenic acid in the leaves of ethanol-extracted Eucommia leaf was in accordance with the internal diffusion kinetics model. The apparent activation energy Ea was 11.46 kJ / mol.