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目的:探讨脑胶质细胞瘤立体定向放射外科(SRS)治疗后加速再增殖的问题。方法:研究1994年4月~1997年2月间21例SRS治疗后复发再手术治疗的病例,本组均行MRI检查、手术切除、病理检查。在MRI片上测量肿瘤的大小。结果:SRS治疗后脑胶质瘤复发迅速,周边脑组织大片水肿,瘤细胞增殖活跃,侵润性增强。结论:(1)中枢神经系统恶性肿瘤的放射治疗也存在加速再增殖的问题;(2)SRS治疗脑胶质瘤应严格掌握适应证。
Objective: To investigate the problem of accelerated re-proliferation after stereotactic radiosurgery (SRS) treatment of glioma. Methods: From April 1994 to February 1997, 21 cases of recurrent and recurrent SRS after SRS were studied. The patients underwent MRI, surgical resection and pathological examination in this group. Tumor size was measured on MRI slices. Results: The brain gliomas recurred rapidly after treatment with SRS, with extensive edema in the surrounding brain tissue. The tumor cells proliferated actively and their invasiveness was enhanced. Conclusions: (1) Radiation therapy of central nervous system malignant tumors also has the problem of accelerating and then proliferating; (2) SRS treatment of glioma should be strictly controlled indications.