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对 6 0例糖尿病 (DM)病人及 2 1例正常人进行了 2 4h尿微量白蛋白 (AIb)、尿视黄醇结合蛋白(RBP)与N -乙酰β -氨基葡萄糖苷酶 (NAG)检测比较研究。结果显示 :2 4h尿AIb与NAG及RBP比较呈显著正相关 (P <0 .0 1) ;尿RBP及尿NAG在普通糖尿病组 (DMA组 )、早期糖尿病肾病组 (DMB组 )及正常对照组间均有显著性差异 (P <0 .0 5,P <0 .0 0 1)。提示NAG与RBP可作为诊断早期糖尿病肾病的敏感指标
24 h urine microalbumin (AIb), urinary retinal binding protein (RBP) and N - acetylglucosaminidase (NAG) were detected in 60 diabetics (DM) and 21 normal controls compare research. The results showed that there was a significant positive correlation between 24 h urinary AIb and NAG and RBP (P <0.01), urinary RBP and urinary NAG in normal diabetic group (DMA group), early diabetic nephropathy group (DMB group) and normal control There was significant difference between the two groups (P <0.05, P <0.01). Tip NAG and RBP can be used as a sensitive indicator of early diagnosis of diabetic nephropathy